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AFP Native Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS537041

MBS537041 is a native protein targeting AFP. Also known as AFP protein. Purified native Human AFP protein More details

$720 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AFP, Native Protein
Full Product Name
AFP protein
Product Gene Name
Product Synonym Names
alpha-Fetoprotein protein; alpha-Fetoprotein antigen
Form/Format
Supplied in 0.1M Phosphate buffer, 0.2M NaCl, pH 7.3, with 0.1% NaN3
Purity/Purification
> 60%
Concentration
10 mg/ml measured by OD280nm (lot specific)
Preparation and Storage
For routine storage aliquot and freeze at -20°C or below.
Molecular Weight
68,678 Da
OMIM
104150
3D Structure
ModBase 3D Structure for P02771
Source Note
Human cord serum
Species
Human
Protein Type
Native
Grade
Standard
Contaminants
None detected by reduced and non-reduced SDS-PAGE (single band).
Biohazard Information
Raw materials tested at the donor level by approved FDA methods and found to be negative for HCV antibodies, HIV-1 and 2 antibodies and HBsAg. Tested by ROCHE EIA.

Product Categories/Family for AFP native protein

Applications Tested/Suitable for AFP native protein
ELISA (EIA)
Application Notes for AFP native protein
Suitable for use as a calibrator in immunoassays or as an immunogen.
Optimal conditions to be determined by end user.

Product References and Citations for AFP native protein

Simultaneous multianalysis for tumor markers by antibody fragments microarray system; Shi-Ping Songa, Bin Lia, Jun Hua, Min-Qian Li (Analytica Chimica Acta: Volume: 510 Issue: 2 Page: 147-152 DOI: 10.1016/j.aca.2004.01.020)
Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein; Young Ju Lee, Seong-Wook Lee (Biochemical and Biophysical Research Communications: Volume: 417 Issue: 1 Page: 521-527 DOI: 10.1016/j.bbrc.2011.11.153)

Other Notes

Small volumes of AFP native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AFP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Alpha-fetoprotein
NCBI Official Synonym Full Names
alpha-fetoprotein
NCBI Official Symbol
AFP
NCBI Official Synonym Symbols
AFPD; FETA; HPAFP
UniProt Protein Name
Alpha-fetoprotein
UniProt Synonym Protein Names
Alpha-1-fetoprotein; Alpha-fetoglobulin
Protein Family
UniProt Gene Name
AFP
UniProt Synonym Gene Names
HPAFP
UniProt Entry Name
FETA_HUMAN
NCBI Protein Information
alpha-fetoprotein

NCBI Summary for AFP

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
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UniProt Comments for AFP

AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; cytoplasm

Molecular Function: metal ion binding

Biological Process: transport; progesterone metabolic process; ovulation from ovarian follicle

Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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