Tight Junction Pathway - Page 21

Band 4.1-like protein 3 (EPB41L3), ELISA Kit

Canine Band 4.1-like protein 3 (EPB41L3) ELISA Kit

(#MBS7229566)

Gene Names:

EPB41L3; 4.1B; DAL1; DAL-1

Other Names:

band 4.1-like protein 3 isoform 1; erythrocyte membrane protein band 4.1-like 3

Host/Reactivities:

Reactivity: Canine

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Angiomotin-Like Protein 1 (AMOTL1), ELISA Kit

Bovine Angiomotin-Like Protein 1 (AMOTL1) ELISA Kit

(#MBS9368390)

Gene Names:

AMOTL1; JEAP

Other Names:

angiomotin-like protein 1 isoform 1; angiomotin like 1

Host/Reactivities:

Reactivity: Bovine

Claudin-9 (CLDN9), ELISA Kit

Goat Claudin-9 (CLDN9) ELISA Kit

(#MBS7232083)

Gene Names:

CLDN9

Other Names:

claudin-9; claudin 9

Host/Reactivities:

Reactivity: Goat

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Claudin-6 (CLDN6), ELISA Kit

Chicken Claudin-6 (CLDN6) ELISA Kit

(#MBS7213373)

Gene Names:

CLDN6

Other Names:

claudin-6; claudin 6

Host/Reactivities:

Reactivity: Chicken

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Claudin-10 (CLDN10), ELISA Kit

Bovine Claudin-10 (CLDN10) ELISA Kit

(#MBS7217628)

Gene Names:

CLDN10; OSP-L; CPETRL3

Other Names:

claudin-10 isoform a_i1; claudin 10

Host/Reactivities:

Reactivity: Bovine

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Claudin 3, Polyclonal Antibody

Rabbit anti Claudin 3 Polyclonal Antibody

(#MBS460193)

Gene Names:

CLDN3; RVP1; HRVP1; C7orf1; CPE-R2; CPETR2

Other Names:

claudin 3

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Mouse, Rat

Purification:

Purified by Epitope Affinity Purification

Isotype/Clone:

Isotype: IgG

Applications:

Immunohistochemistry (IHC), Western Blot (WB)

AMOTL1, siRNA

AMOTL1 siRNA (Human)

(#MBS8239530)

Gene Names:

AMOTL1; JEAP

Other Names:

Angiomotin-like protein 1; angiomotin-like protein 1 isoform 2; angiomotin like 1

Host/Reactivities:

Host: Synthetic / Reactivity: Human

Purification:

> 97%

Applications:

RNA Interference (RNAi)

CLDN8, Polyclonal Antibody

CLDN8 Polyclonal Antibody

(#MBS2525575)

Gene Names:

CLDN8

Other Names:

Claudin 8; Claudin-8; CLD8; HEL S 79

Host/Reactivities:

Host: Rabbit / Reactivity: Human

Purification:

Affinity purification

Isotype/Clone:

Isotype: IgG

Applications:

ELISA (EIA), Immunohistochemistry (IHC)

Tight junction protein 1, ELISA Kit

Chicken tight junction protein 1 (ZO1) ELISA Kit

(#MBS2604354)

Gene Names:

ZO1; TJP2; ZO2; X104; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11

Other Names:

tight junction protein ZO-2 isoform 1; tight junction protein 2

Host/Reactivities:

Reactivity: Chicken

TJP2, Polyclonal Antibody

TJP2, phosphorylated (S978) (TJP2, X104, ZO2, Tight junction protein ZO-2, Tight junction protein 2, Zona occludens protein 2, Zonula occludens protein 2)

(#MBS647848)

Gene Names:

TJP2; ZO2; X104; DFNA51; DUP9q21.11; C9DUPq21.11

Other Names:

Anti -TJP2; phosphorylated (S978) (TJP2; Tight junction protein ZO-2; Tight junction protein 2; Zona occludens protein 2; Zonula occludens protein 2); tight junction protein ZO-2 isoform 4

Host/Reactivities:

Host: Rabbit / Reactivity: Human

Purification:

Affinity PurifiedPurified by Protein A affinity chromatography.

Isotype/Clone:

Isotype: IgG

Applications:

ELISA (EL/EIA), Gel Shift Assay (GS/EMSA)

RAB3B, Polyclonal Antibody

RAB3B (Ras-related Protein Rab-3B)

(#MBS643380)

Gene Names:

RAB3B

Other Names:

Anti -RAB3B (Ras-related Protein Rab-3B); member RAS oncogene family

Host/Reactivities:

Host: Mouse / Reactivity: Human

Purification:

Affinity PurifiedPurified by Protein A affinity chromatography.

Isotype/Clone:

Isotype: IgG

Applications:

Western Blot (WB)

Myosin Heavy Chain 4, Skeletal Muscle (MYH4), ELISA Kit

Human Myosin Heavy Chain 4, Skeletal Muscle (MYH4) ELISA Kit

(#MBS4501244)

Gene Names:

MYH4; MYH2B; MyHC-2B; MyHC-IIb

Other Names:

Myosin heavy chain 2b; Myosin heavy chain; skeletal muscle; fetal; myosin-4; myosin heavy chain 4

Host/Reactivities:

Reactivity: Human

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates or Other Biological Fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.127ng/mL

Myosin 7, Polyclonal Antibody

Rabbit anti-Myosin 7 Antibody

(#MBS4510671)

Gene Names:

MYH7; CMH1; MPD1; SPMD; SPMM; CMD1S; MYHCB

Other Names:

Myosin-7; Myosin heavy chain 7; Myosin heavy chain slow isoform; MyHC-slow; Myosin heavy chain; cardiac muscle beta isoform; MyHC-beta; myosin; heavy chain 7; cardiac muscle; beta

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Mouse, Rat

Purification:

The antibody was purified by immunogen affinity chromatography.

Applications:

Western Blot (WB), Immunohistochemistry (IHC)

Myosin 13 (MYH13), ELISA Kit

Canine Myosin 13 (MYH13) ELISA Kit

(#MBS9354694)

Gene Names:

MYH13; MyHC-eo; MyHC-IIL

Other Names:

myosin-13; myosin; heavy chain 13; skeletal muscle

Host/Reactivities:

Reactivity: Canine

Claudin-3 (CLDN3), ELISA Kit

Sheep Claudin-3 (CLDN3) ELISA Kit

(#MBS7227779)

Gene Names:

CLDN3; RVP1; HRVP1; C7orf1; CPE-R2; CPETR2

Other Names:

claudin-3; claudin 3

Host/Reactivities:

Reactivity: Sheep

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

1.0-25ng/mL

Sensitivity

0.1ng/mL

Claudin-17 (CLDN17), ELISA Kit

Goat Claudin-17 (CLDN17) ELISA Kit

(#MBS7213553)

Gene Names:

CLDN17

Other Names:

claudin-17; claudin 17

Host/Reactivities:

Reactivity: Goat

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Myosin Heavy Chain 2 (MYH2), Polyclonal Antibody

Polyclonal Antibody to Myosin Heavy Chain 2 (MYH2)

(#MBS2111974)

Gene Names:

MYH2; IBM3; MYH2A; MYHSA2; MYHas8; MyHC-2A; MyHC-IIa

Other Names:

Myosin Heavy Chain 2; Skeletal Muscle; Adult; myosin-2; myosin; heavy chain 2

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Pig

Purification:

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Applications:

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Myosin Heavy Chain 11, Smooth Muscle, ELISA Kit

Goat Myosin Heavy Chain 11, Smooth Muscle ELISA Kit

(#MBS084755)

Gene Names:

MYH11; MYH7; CMH1; MPD1; SPMD; SPMM; CMD1S; MYHCB

Other Names:

Myosin-7; myosin; heavy chain 7; cardiac muscle; beta

Host/Reactivities:

Reactivity: Goat

View Details

Erythrocyte Membrane Protein Band 4.1 (EPB41), Polyclonal Antibody

FITC-Linked Polyclonal Antibody to Erythrocyte Membrane Protein Band 4.1 (EPB41)

(#MBS2064379)

Gene Names:

EPB41; HE; EL1; 4.1R

Other Names:

Elliptocytosis 1; RH-linked; erythrocyte membrane protein band 4.1 (elliptocytosis 1; RH-linked); isoform CRA_d; erythrocyte membrane protein band 4.1

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Mouse, Rat, Pig

Applications:

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Angiomotin-Like Protein 1 (AMOTL1), ELISA Kit

Mouse Angiomotin-Like Protein 1 (AMOTL1) ELISA Kit

(#MBS9349067)

Gene Names:

AMOTL1; JEAP

Other Names:

angiomotin-like protein 1 isoform 1; angiomotin like 1

Host/Reactivities:

Reactivity: Mouse

Band 4.1-like protein 2 (EPB41L2), ELISA Kit

Guinea pig Band 4.1-like protein 2 (EPB41L2) ELISA Kit

(#MBS7224613)

Gene Names:

EPB41L2; 4.1G; 4.1-G

Other Names:

band 4.1-like protein 2 isoform a; erythrocyte membrane protein band 4.1-like 2

Host/Reactivities:

Reactivity: Guinea Pig

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Protein Shroom3 (SHROOM3), ELISA Kit

Bovine Protein Shroom3 (SHROOM3) ELISA Kit

(#MBS9344474)

Gene Names:

SHROOM3; SHRM; APXL3; ShrmL; MSTP013

Other Names:

protein Shroom3; shroom family member 3

Host/Reactivities:

Reactivity: Bovine

Myosin Heavy Chain 2, Skeletal Muscle, Adult, ELISA Kit

Hamster Myosin Heavy Chain 2, Skeletal Muscle, Adult ELISA Kit

(#MBS066333)

Gene Names:

MYH2; IBM3; MYH2A; MYHSA2; MYHas8; MyHC-2A; MyHC-IIa

Other Names:

myosin-2; myosin; heavy chain 2; skeletal muscle; adult

Host/Reactivities:

Reactivity: Hamster

MPP5, Polyclonal Antibody

MPP5 Antibody, Biotin conjugated

(#MBS7050910)

Gene Names:

MPP5; PALS1

Other Names:

MAGUK p55 subfamily member 5; MAGUK p55 subfamily member 5 isoform 2; membrane palmitoylated protein 5

Host/Reactivities:

Host: Rabbit / Reactivity: Human

Purification:

>95%, Protein G purified

Isotype/Clone:

Isotype: IgG

Applications:

ELISA (EIA)

Claudin-6, Polyclonal Antibody

Claudin-6 Polyclonal Antibody

(#MBS2537869)

Gene Names:

CLDN6

Other Names:

Claudin-6; Skullin; claudin 6

Host/Reactivities:

Host: Rabbit / Reactivity: Human

Purification:

Antigen Affinity Purified

Isotype/Clone:

Isotype: IgG

Applications:

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

Claudin 6, Polyclonal Antibody

Claudin 6 (Phospho-Tyr219) Antibody

(#MBS9412201)

Gene Names:

CLDN6

Other Names:

claudin 6; claudin-6; CLD6; Skullin 2

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Mouse

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho ...

Applications:

Western Blot (WB)

Claudin 11 (CLDN11), ELISA Kit

Human Claudin 11 (CLDN11) ELISA Kit

(#MBS163233)

Gene Names:

CLDN11; OSP; OTM

Other Names:

claudin-11 isoform 2; claudin 11

Host/Reactivities:

Reactivity: Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, cell lysates, tissue homogenates

Detection Range

1ng/ml - 40ng/ml

Sensitivity

0.46ng/ml

Tight junction protein ZO-2 (TJP2), Recombinant Protein

Recombinant Human Tight junction protein ZO-2 (TJP2) , partial

(#MBS1463473)

Gene Names:

TJP2; ZO2; X104; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11

Other Names:

tight junction protein ZO-2 isoform 4; tight junction protein 2

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

View Details

SHROOM3, Blocking Peptide

SHROOM3 Peptide

(#MBS153821)

Gene Names:

SHROOM3; SHRM; APXL3; ShrmL; MSTP013

Other Names:

KIAA1481; Protein Shroom3; Shroom-related protein; hShrmL; shroom family member 3

Applications:

Blocking (BL)

InaD-Like Protein (INADL), ELISA Kit

Fish InaD-Like Protein (INADL) ELISA Kit

(#MBS9379908)

Gene Names:

INADL; PATJ; Cipp; hINADL; InaD-like

Other Names:

inaD-like protein; crumbs cell polarity complex component

Host/Reactivities:

Reactivity: Fish

View Details

EPB41L2, Antibody

EPB41L2 Antibody

(#MBS8514554)

Gene Names:

EPB41L2; 4.1G; 4.1-G

Other Names:

Band 4.1-like protein 2; DKFZp781D1972; DKFZp781H1755; E41L2; erythrocyte membrane protein band 4.1 like-protein 2; erythrocyte membrane protein band 4.1-like 2; Generally expressed protein 4.1; band ...

Host/Reactivities:

Reactivity: Human

Purification:

Immunogen affinity purified

Applications:

Western Blot (WB), Immunohistochemistry (IHC)

Claudin 23 (CLDN23), ELISA Kit

Human Claudin 23 (CLDN23) ELISA Kit

(#MBS160395)

Gene Names:

CLDN23; CLDNL; hCG1646163

Other Names:

claudin-23; claudin 23

Host/Reactivities:

Reactivity: Human

Assay Type

Quantitative Sandwich

Samples

Serum, Plasma, Cell Culture Supernates, Cell Lysates, Tissue Homogenates

Detection Range

0.05ng/ml-20ng/ml

Sensitivity

0.013ng/ml

CLDN10, cDNA Clone

CLDN10 cDNA Clone

(#MBS1272203)

Gene Names:

CLDN10; OSP-L; CPETRL3

Other Names:

Homo sapiens claudin 10; mRNA; claudin 10

0.01 mg Plasmid + 0.2 mL Glycerol-Stock

$235

5x0.01 mg Plasmid + 5x0.2 mL Glycerol-Stock

$1050

View Details

Band 4.1-like protein 2 (EPB41L2), ELISA Kit

Monkey Band 4.1-like protein 2 (EPB41L2) ELISA Kit

(#MBS7251061)

Gene Names:

EPB41L2; 4.1G; 4.1-G

Other Names:

band 4.1-like protein 2 isoform a; erythrocyte membrane protein band 4.1-like 2

Host/Reactivities:

Reactivity: Monkey

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

ZO2, Polyclonal Antibody

ZO2 Antibody

(#MBS9435068)

Gene Names:

ZO2; TJP2; X104; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11

Other Names:

C9DUPq21.11 antibody; DFNA51 antibody; DUP9q21.11 antibody; Friedreich ataxia region gene X104 (tight junction protein ZO-2) antibody; MGC26306 antibody; PFIC4 antibody; Tight junction protein 2 antib...

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Mouse

Purification:

Peptide affinity purified

Applications:

Western Blot (WB), Immunocytochemistry (ICC)

Protein Shroom3 (SHROOM3), ELISA Kit

Rat Protein Shroom3 (SHROOM3) ELISA Kit

(#MBS9346797)

Gene Names:

SHROOM3; SHRM; APXL3; ShrmL; MSTP013

Other Names:

protein Shroom3; shroom family member 3

Host/Reactivities:

Reactivity: Rat

Myosin-pan, Blocking Peptide

Myosin-pan (AcK505) Blocking Peptide

(#MBS8247820)

Gene Names:

MYH1; MYHa; HEL71; MYHSA1; MyHC-2x; MyHC-2X/D

Other Names:

Myosin-1; Myosin heavy chain 1; Myosin heavy chain 2x; Myosin heavy chain IIx/d; MyHC-IIx/d; Myosin heavy chain; skeletal muscle; adult 1; MYH2; MYHSA2; Myosin-2; Myosin heavy chain 2; Myosin heavy ch...

Host/Reactivities:

Host: Synthetic / Reactivity: Human, Mouse, Rat, Bovine, Dog, Pig

Purity:

>85%

Applications:

Blocking (BL)

Myosin Light Chain 5, Recombinant Protein

Recombinant Human Myosin Light Chain 5 (1-173 a.a.)

(#MBS144350)

Gene Names:

MYL5

Other Names:

MYL5 (1-173 a.a.) Human; Myosin Light Chain 5 (1-173 a.a.) Human Recombinant; Myosin light chain 5; Myosin regulatory light chain 5; Superfast myosin regulatory light chain 2; MYLC2; MyLC-2; MYL5 (1-1...

Host/Reactivities:

Host: E Coli

Purity:

Greater than 90.0% as determined by SDS-PAGE.

Myosin Heavy Chain 2, Skeletal Muscle, Adult, ELISA Kit

Goat Myosin Heavy Chain 2, Skeletal Muscle, Adult ELISA Kit

(#MBS054081)

Gene Names:

MYH2; IBM3; MYH2A; MYHSA2; MYHas8; MyHC-2A; MyHC-IIa

Other Names:

myosin-2; myosin; heavy chain 2; skeletal muscle; adult

Host/Reactivities:

Reactivity: Goat

View Details

Claudin-9 (CLDN9), ELISA Kit

Rat Claudin-9 (CLDN9) ELISA Kit

(#MBS7253630)

Gene Names:

CLDN9

Other Names:

claudin-9; claudin 9

Host/Reactivities:

Reactivity: Rat

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

1.0-25ng/mL

Sensitivity

0.1ng/ml

Claudin-10, Polyclonal Antibody

Claudin-10 Polyclonal Antibody

(#MBS8521925)

Gene Names:

CLDN10; OSPL; HELIX; OSP-L; CPETRL3

Other Names:

claudin-10 isoform a_i1; claudin 10

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D), Recombinant Protein

Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D)

(#MBS1313653)

Gene Names:

PPP2R2D; B55D; MDS026; B55delta

Other Names:

serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform b; protein phosphatase 2 regulatory subunit Bdelta

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

0.02 mg (Baculovirus)

$1600

0.02 mg (Mammalian-Cell)

0.1 mg (Mammalian-Cell)

0.5 mg (Mammalian-Cell)

$7455

More Sizes/Prices

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PARD6B, Antibody

PARD6B Antibody

(#MBS8514981)

Gene Names:

PARD6B; PAR6B

Other Names:

cytoplasm; plasma membrane; cell junction; tight junction; partitioning defective 6 homolog beta; par-6 family cell polarity regulator beta

Host/Reactivities:

Reactivity: Human, Mouse

Purification:

Immunogen affinity purified

Applications:

Western Blot (WB)

Myosin 13 (MYH13), ELISA Kit

Rabbit Myosin 13 (MYH13) ELISA Kit

(#MBS9369352)

Gene Names:

MYH13; MyHC-eo; MyHC-IIL

Other Names:

myosin-13; myosin; heavy chain 13; skeletal muscle

Host/Reactivities:

Reactivity: Rabbit

View Details

LLGL2, Polyclonal Antibody

LLGL2 Polyclonal Antibody

(#MBS2527548)

Gene Names:

LLGL2; HGL; LGL2

Other Names:

LLGL2 protein; lethal giant larvae homolog 2 (Drosophila)

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Mouse, Rat

Purification:

Antigen affinity purification

Isotype/Clone:

Isotype: IgG

Applications:

ELISA (EIA), Immunohistochemistry (IHC)

Erythrocyte Membrane Protein Band 4.1 (EPB41), Polyclonal Antibody

APC-Linked Polyclonal Antibody to Erythrocyte Membrane Protein Band 4.1 (EPB41)

(#MBS2064377)

Gene Names:

EPB41; HE; EL1; 4.1R

Other Names:

Elliptocytosis 1; RH-linked; erythrocyte membrane protein band 4.1 (elliptocytosis 1; RH-linked); isoform CRA_d; erythrocyte membrane protein band 4.1

Host/Reactivities:

Host: Rabbit / Reactivity: Human, Mouse, Rat, Pig

Applications:

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Claudin-18.2 (CLDN18.2), Recombinant Protein

Recombinant Human Claudin-18.2 (CLDN18.2)-VLPs (Active)

(#MBS9019696)

Gene Names:

CLDN18.2; CLDN18; SFTA5; SFTPJ; DKFZp564B2062

Other Names:

claudin-18 isoform 2; claudin 18

Host/Reactivities:

Host: Mammalian cell

Purity:

The purity information is not available for VLPs proteins.

0.02 mg (Mammalian-Cell)

$535

0.1 mg (Mammalian-Cell)

$930

1 mg (Mammalian-Cell)

$4395

5x1 mg (Mammalian-Cell)

$19875

View Details

Antigen presenting glycoprotein CD1d (CD1D), ELISA Kit

Human Antigen presenting glycoprotein CD1d (CD1D) ELISA Kit

(#MBS7253841)

Gene Names:

CD1D; R3; CD1A; R3G1

Other Names:

antigen-presenting glycoprotein CD1d isoform 1; CD1d molecule

Host/Reactivities:

Reactivity: Human

Samples

Serum, Plasma, Cell Culture Supernatants, Body Fluid and Tissue Homogenate

RAB3B, Polyclonal Antibody

RAB3B Antibody; Biotin conjugated

(#MBS7004523)

Gene Names:

RAB3B

Other Names:

Ras-related protein Rab-3B; member RAS oncogene family

Host/Reactivities:

Host: Rabbit / Reactivity: Human, mouse

Purification:

>95%,Protein G purified

Isotype/Clone:

Isotype: IgG

Applications:

ELISA (EIA)

MYH7, Blocking Peptide

MYH7 Antibody (N-term) Blocking Peptide

(#MBS9222741)

Gene Names:

MYH7; MYHCB; CMH1; MPD1; SPMD; SPMM; CMD1S

Other Names:

Myosin-7; Myosin heavy chain 7; Myosin heavy chain slow isoform; MyHC-slow; Myosin heavy chain; cardiac muscle beta isoform; MyHC-beta; myosin; heavy chain 7; cardiac muscle; beta