B Cell Differentiation Factor (BCDE) ELISA Kit for Plant

Name: Plant BCDE ELISA Kit; B Cell Differentiation Factor; MyBioSource
Brand: MyBioSource
SKU: MBS9381228
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9381228

MBS9381228 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the B Cell Differentiation Factor (BCDE) ELISA Kit target analytes in biological samples. The concentration gradients of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

B Cell Differentiation Factor (BCDE), ELISA Kit

Full Product Name

Plant B Cell Differentiation Factor (BCDE) ELISA Kit

Product Gene Name

BCDE elisa kit

Species Reactivity

Plant

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

15,238 Da

OMIM

147850

3D Structure

ModBase 3D Structure for P05113

Other Notes

Small volumes of BCDE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BCDE. It may not necessarily be applicable to this product.

NCBI GI #

29393

NCBI GeneID

3567

NCBI Accession #

CAA31211.1

UniProt Primary Accession #

P05113

UniProt Secondary Accession #

Q13840

UniProt Related Accession #

P05113

NCBI Official Full Name

B cell differentiation factor I

NCBI Official Synonym Full Names

interleukin 5

NCBI Official Symbol

IL5

NCBI Official Synonym Symbols

EDF; TRF; IL-5

UniProt Protein Name

Interleukin-5

UniProt Synonym Protein Names

B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF

UniProt Gene Name

IL5

UniProt Synonym Gene Names

IL-5; TRF

UniProt Entry Name

IL5_HUMAN

NCBI Protein Information

interleukin-5

NCBI Summary for BCDE

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]

UniProt Comments for BCDE

IL5: Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. Belongs to the IL-5 family.

Protein type: Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity

Biological Process: cytokine and chemokine mediated signaling pathway; MAPKKK cascade; positive regulation of B cell proliferation; positive regulation of immunoglobulin secretion; positive regulation of peptidyl-tyrosine phosphorylation

Research Articles on BCDE

1. high levels of IL-33 and a high IL-33/soluble ST2 ratio correlates with elevated levels of IFN-gamma, TNF-alpha and IL-17alpha as well as IL-5, demonstrating that IL-33 has pleiotropic effects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with BCDE elisa kit

Reference Product	PubMed Publications
IL4 elisa kit	>261 publications with BCDE and IL4
IL2 elisa kit	>112 publications with BCDE and IL2
IL3 elisa kit	>53 publications with BCDE and IL3
JUN elisa kit	>50 publications with BCDE and JUN
IL9 elisa kit	>31 publications with BCDE and IL9
GATA3 elisa kit	>27 publications with BCDE and GATA3
IL5RA elisa kit	>12 publications with BCDE and IL5RA
STAT6 elisa kit	>11 publications with BCDE and STAT6
CSF2RB elisa kit	>2 publications with BCDE and CSF2RB

Pathways associated with BCDE elisa kit

Products by Pathway	Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Asthma Pathway antibodies	Asthma Pathway Diagram
Asthma Pathway antibodies	Asthma Pathway Diagram
Autoimmune Thyroid Disease Pathway antibodies	Autoimmune Thyroid Disease Pathway Diagram
Autoimmune Thyroid Disease Pathway antibodies	Autoimmune Thyroid Disease Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies	Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram

Diseases associated with BCDE elisa kit

Disease Name	Pubmed Publications
Hypersensitivity Antibodies	>169 publications with BCDE and Hypersensitivity
Inflammation Antibodies	>144 publications with BCDE and Inflammation
Asthma Antibodies	>140 publications with BCDE and Asthma
Respiratory Hypersensitivity Antibodies	>117 publications with BCDE and Respiratory Hypersensitivity
Lung Diseases Antibodies	>115 publications with BCDE and Lung Diseases
Eosinophilia Antibodies	>84 publications with BCDE and Eosinophilia
Necrosis Antibodies	>72 publications with BCDE and Necrosis
Fibrosis Antibodies	>15 publications with BCDE and Fibrosis
Hyperplasia Antibodies	>14 publications with BCDE and Hyperplasia
Bronchial Hyperreactivity Antibodies	>13 publications with BCDE and Bronchial Hyperreactivity

Organs/Tissues associated with BCDE elisa kit

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>9 publications with BCDE and Thymus