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CTLA4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5313088

CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CTLA4, Polyclonal Antibody
Full Product Name
CTLA4 Antibody
Product Gene Name
Product Synonym Names
Affintiy Purified Rabbit Polyclonal CTLA4 Antibody; CTLA4 antibody; CTLA 4 antibody; CTLA-4 antibody; Cytotoxic T-lymphocyte protein 4 antibody; CD152 antibody; N terminal CTLA4 antibody; CD152
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Liquid in PBS with 0.09% (W/V) Sodium Azide
Purity/Purification
Purified through a protein A column, followed by peptide affinity purification
Concentration
0.5 mg/ml (lot specific)
Specificity
N-terminal CTLA4 (CD152)
Preparation and Storage
Store at 2-8 degree C for short periods. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Immunogen
CTLA4 antibody (N terminal) was raised in Rabbit using a KLH conjugated synthetic peptide between 57-86 amino acids from the N-terminal region of human IDDM12 as the immunogen

Product Categories/Family for anti-CTLA4 antibody

Applications Tested/Suitable for anti-CTLA4 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-CTLA4 antibody
ELISA: 1:1000
IHC: 1:1:50-100
WB: 1:100-500

Western Blot (WB) of anti-CTLA4 antibody

Western blot analysis using CTLA4 antibody (N terminal)in WiDr cell lysates (35ug/lane).This demonstrates the CTLA4 antibody detected the CTLA4 protein (arrow)
Rabbit Anti-CTLA4 Polyclonal Antibody – Cat# MBS5313088

Immunohistochemistry (IHC) of anti-CTLA4 antibody

Immunohistochemical staining in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Rabbit Anti-CTLA4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS5313088

Other Notes

Small volumes of anti-CTLA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CTLA4 purchase

MBS5313088 is an antibody targeting CTLA4. Also known as CTLA4 Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CTLA4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Related Accession #
NCBI Official Full Name
CTLA4
NCBI Official Synonym Full Names
cytotoxic T-lymphocyte associated protein 4
NCBI Official Symbol
CTLA4
NCBI Official Synonym Symbols
CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
NCBI Protein Information
cytotoxic T-lymphocyte protein 4

NCBI Summary for CTLA4

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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