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DCR-1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6471977

MBS6471977 is an antibody targeting Dcr-1. Also known as Dcr-1, ID (Endoribonuclease dcr-1, dcr-1, K12H4.8) (APC). Reactive in C. elegans. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dcr-1, Polyclonal Antibody
Full Product Name
Dcr-1, ID (Endoribonuclease dcr-1, dcr-1, K12H4.8) (APC)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
C. elegans
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein G Affinity Chromatography.
Specificity
Recognizes c. elegans Dcr-1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
210.924
3D Structure
ModBase 3D Structure for P34529
Immunogen
Synthetic peptide selected from the central region of C. elegans Dcr-1 (KLH).
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-Dcr-1 antibody

Applications Tested/Suitable for anti-Dcr-1 antibody
Western Blot (WB), FLISA
Application Notes for anti-Dcr-1 antibody
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-Dcr-1 antibody

Western blot analysis of Dcr-1 antibody (Center) in CEM cell line lysates (35ug/lane). Dcr-1 (arrow) was detected using the purified Pab.
Rabbit Anti-DCR-1 Polyclonal Antibody – Cat# MBS6471977

Product References and Citations for anti-Dcr-1 antibody

1. Duchaine TF, et al. 2006. Cell 124:343-354. 2. Denli AM, et al. 2004. Nature 432:231-235. 3. Tabara H, et al. 2002. Cell 109:861-871. 4. Grishok A, et al. 2001. Cell 106:23-34. 5. Knight SW, et al. 2001. Science 293:2269-2271.

Other Notes

Small volumes of anti-Dcr-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Dcr-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Death-promoting deoxyribonuclease
NCBI Official Symbol
dcr-1
UniProt Protein Name
Endoribonuclease dcr-1
Protein Family
UniProt Gene Name
dcr-1
UniProt Synonym Gene Names
tDCR-1
NCBI Protein Information
Death-promoting deoxyribonuclease

UniProt Comments for Dcr-1

Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway (PubMed:11641272, PubMed:20223951). It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs (PubMed:11641272, PubMed:20223951). Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing (PubMed:11641272).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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