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DOCK11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5315801

DOCK11 exhibits the same domain arrangement as other members of the DOCK-D/Zizimin subfamily and shares the highest level of sequence identity with Dock9. It contains a DHR2 domain which mediates GEF activity and a DHR1 domain which may interact with membrane… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DOCK11, Polyclonal Antibody
Full Product Name
DOCK11 Antibody
Product Gene Name
Product Synonym Names
Purified Polyclonal DOCK11 Antibody; Polyclonal DOCK11 antibody; Anti-DOCK11 antibody; ZIZ2 antibody; Dedicator of cytokinesis protein 11 antibody; Activated Cdc42-associated guanine nucleotide exchange factor antibody; ACG antibody; Zizimin-2 antibody
Clonality
Polyclonal
Host
Rabbit
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Purity/Purification
Immunogen Affinity Chromatography
Specificity
Recognizes endogenous levels of DOCK11 protein
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
OMIM
300681
3D Structure
ModBase 3D Structure for Q5JSL3
Immunogen
DOCK11 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DOCK11 as the immunogen
Cross-Reactivity
Mouse, Rat, Pig

Product Categories/Family for anti-DOCK11 antibody

Applications Tested/Suitable for anti-DOCK11 antibody
Western Blot (WB)
Application Notes for anti-DOCK11 antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-DOCK11 antibody

Western blot analysis of DOCK11 expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Rabbit Anti-DOCK11 Polyclonal Antibody – Cat# MBS5315801

Other Notes

Small volumes of anti-DOCK11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DOCK11 purchase

MBS5315801 is an antibody targeting DOCK11. Also known as DOCK11 Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DOCK11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dedicator of cytokinesis protein 11
NCBI Official Synonym Full Names
dedicator of cytokinesis 11
NCBI Official Symbol
DOCK11
NCBI Official Synonym Symbols
ACG; ZIZ2; bB128O4.1
UniProt Protein Name
Dedicator of cytokinesis protein 11
UniProt Synonym Protein Names
Activated Cdc42-associated guanine nucleotide exchange factor; ACG; Zizimin-2
UniProt Gene Name
DOCK11
UniProt Synonym Gene Names
ZIZ2; ACG
UniProt Entry Name
DOC11_HUMAN
NCBI Protein Information
dedicator of cytokinesis protein 11

UniProt Comments for DOCK11

DOCK11: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Belongs to the DOCK family.

Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: cytosol

Molecular Function: Rho guanyl-nucleotide exchange factor activity; Rho GTPase binding

Biological Process: small GTPase mediated signal transduction; blood coagulation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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