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DUSP26 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5312248

MBS5312248 is an antibody targeting DUSP26. Also known as DUSP26 Antibody. Host: Rabbit. More details

$1565 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DUSP26, Polyclonal Antibody
Full Product Name
DUSP26 Antibody
Product Gene Name
anti-DUSP26 antibody
Product Synonym Names
Affinity Purified Rabbit Polyclonal DUSP26 Antibody; Polyclonal DUSP26 antibody; Anti-DUSP26 antibody; DUSP 26; DUSP26 antibody; MGC2627 antibody; MGC1136 antibody; DUSP-26; DUSP24 antibody; MKP8 antibody; SKRP3 antibody; DSP-4 antibody; MAP kinase phosphatase 8 antibody; mitogen-activated protein kinase phosphatase 8 antibody; LDP-4 antibody; DUSP 26 antibody; low-molecular-mass dual-specificity phosphatase 4 antibody; DUSP-26 antibody; NATA1 antibody; DUSP26
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Purity/Purification
Antigen-Affinity Chromatography
Concentration
1.01 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
24 kDa
3D Structure
ModBase 3D Structure for Q9BV47
Cross-Reactivity
Human, Mouse
Applications Tested/Suitable for anti-DUSP26 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes for anti-DUSP26 antibody
IF: 1:100-1:500
ICC: 1:100-1:500
WB: 1:500-1:3000

Western Blot (WB) of anti-DUSP26 antibody

Western blot analysis of 30 ug of whole cell lysate (A: IMR32) using a 12% SDS PAGE gel and DUSP26 antibody at a dilution of 1:500
Rabbit Anti-DUSP26 Polyclonal Antibody – Cat# MBS5312248

Immunofluorescence (IF) of anti-DUSP26 antibody

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using DUSP26 antibody at 1:200 dilution.
Rabbit Anti-DUSP26 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS5312248

Western Blot (WB) of anti-DUSP26 antibody

Western blot analysis of 50 ug of whole cell lysate (A: mouse brain) using a 12% SDS PAGE gel and DUSP26 antibody at a dilution of 1:500
Rabbit Anti-DUSP26 Polyclonal Antibody, Western Blot (WB) – Cat# MBS5312248

Other Notes

Small volumes of anti-DUSP26 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DUSP26. It may not necessarily be applicable to this product.

NCBI GI #
13128968
UniProt Primary Accession #
Q9BV47
GenBank Nucleotide #
NP_076930.1
NCBI Official Full Name
dual specificity protein phosphatase 26
UniProt Protein Name
Dual specificity protein phosphatase 26
UniProt Synonym Protein Names
Dual specificity phosphatase SKRP3; Low-molecular-mass dual-specificity phosphatase 4; DSP-4; LDP-4; Mitogen-activated protein kinase phosphatase 8; MAP kinase phosphatase 8; MKP-8; Novel amplified gene in thyroid anaplastic cancer
Protein Family
Dual specificity protein phosphatase
UniProt Gene Name
DUSP26
UniProt Synonym Gene Names
DUSP24; LDP4; MKP8; NATA1; SKRP3; DSP-4; LDP-4; MAP kinase phosphatase 8; MKP-8
UniProt Entry Name
DUS26_HUMAN

UniProt Comments for DUSP26

DUSP26: Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, dual-specificity; Motility/polarity/chemotaxis; EC 3.1.3.48; EC 3.1.3.16

Chromosomal Location of Human Ortholog: 8p12

Cellular Component: Golgi apparatus; mitochondrion; cytoplasm; nucleus

Molecular Function: protein binding; p53 binding; phosphoserine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: positive regulation of cell adhesion; negative regulation of transcription from RNA polymerase II promoter; protein amino acid dephosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DUSP26 antibody

 Reference Product  PubMed Publications
 HSF4 antibody  >1 publications with DUSP26 and HSF4

Diseases associated with anti-DUSP26 antibody

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >1 publications with DUSP26 and Lung Diseases
 Cataract Antibodies  >1 publications with DUSP26 and Cataract
 Liver Diseases Antibodies  >1 publications with DUSP26 and Liver Diseases

Organs/Tissues associated with anti-DUSP26 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with DUSP26 and Brain
 Thyroid Antibodies  >2 publications with DUSP26 and Thyroid
 Liver Antibodies  >1 publications with DUSP26 and Liver
 Lung Antibodies  >1 publications with DUSP26 and Lung
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