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EGFR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5309765

The epidermal growth factor receptor (EGFR) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by… More details

$710 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
EGFR, Polyclonal Antibody
Full Product Name
EGFR antibody
Product Gene Name
anti-EGFR antibody
Product Synonym Names
Rabbit polyclonal EGFR antibody; Polyclonal EGFR antibody; Anti-EGFR antibody; Epidermal Growth Factor antibody; Egf receptor antibody; egf-r antibody; v-erb-b homolog antibody; egfr antibody; panitumumab antibody; epidermal growth factor receptor antibody; Ab 869 antibody; erbb1 antibody
Clonality
Polyclonal
Host
Rabbit
Form/Format
Liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl,0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified by immunoaffinity chromatography.
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Molecular Weight
153,700 Da
3D Structure
ModBase 3D Structure for P04412
Immunogen
EGFR antibody was raised in Rabbit using the peptide sequence around aa 867~871 (K-E-Y-H-A) derived from Human EGFR as the immunogen.
Cross-Reactivity
Human, Mouse, Rat

Product Categories/Family for anti-EGFR antibody

Cytokines & Growth Factors
Applications Tested/Suitable for anti-EGFR antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-EGFR antibody
IHC: 1:50-1:100
WB: 1:500-1:1000

Immunohistochemistry (IHC) of anti-EGFR antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR antibody (left) or the same antibody preincubated with with blocking peptide (right)
Rabbit Anti-EGFR Polyclonal Antibody – Cat# MBS5309765

Western Blot (WB) of anti-EGFR antibody

Western Blot analysis of extracts from HUVEC and MDA cells using EGFR antibody
Rabbit Anti-EGFR Polyclonal Antibody, Western Blot (WB) – Cat# MBS5309765

Other Notes

Small volumes of anti-EGFR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EGFR purchase

MBS5309765 is an antibody targeting EGFR. Also known as EGFR antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EGFR. It may not necessarily be applicable to this product.

NCBI GI #
17136536
NCBI GeneID
37455
NCBI Accession #
NP_476759.1
UniProt Primary Accession #
P04412
UniProt Secondary Accession #
O18370; O61601; P81868; Q9W2G0
GenBank Nucleotide #
NM_057411.4
NCBI Official Full Name
epidermal growth factor receptor, isoform B
NCBI Official Synonym Full Names
Epidermal growth factor receptor
NCBI Official Symbol
Egfr
NCBI Official Synonym Symbols
C-erb; c-erbB; CG10079; D-Egf; d-egf-r; D-EGFR; degfr; dEgfr; dEGFr; dEGFR; Degfr; DEgfr; DEGFR; dEGFR1; der; Der; DER; DER flb; DER/EGFR; DER/top; DER/torpedo; DER1; DmelCG10079; DmHD-33; EC2-4; EFG-R; Egf; Egf-r; EGF-R; egfr; EgfR; EGfr; EGFr; EGFR; EK2
UniProt Protein Name
Epidermal growth factor receptor
UniProt Synonym Protein Names
Drosophila relative of ERBB; Gurken receptor; Protein torpedo
Protein Family
Epidermal growth factor receptor
UniProt Gene Name
Egfr
UniProt Synonym Gene Names
c-erbB; DER; top; Egfr
NCBI Protein Information
epidermal growth factor receptor

UniProt Comments for EGFR

Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production of cuticle. Required for embryonic epithelial tissue repair.
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Research Articles on EGFR

1. Graf functions to downregulate EGFR signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-EGFR antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Dorso-ventral Axis Formation Pathway antibodies  Dorso-ventral Axis Formation Pathway Diagram
 Dorso-ventral Axis Formation Pathway antibodies  Dorso-ventral Axis Formation Pathway Diagram
 Downregulation Of ERBB2:ERBB3 Signaling Pathway antibodies  Downregulation Of ERBB2:ERBB3 Signaling Pathway Diagram

Diseases associated with anti-EGFR antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >9013 publications with EGFR and Carcinoma
 Lung Neoplasms Antibodies  >4934 publications with EGFR and Lung Neoplasms
 Adenocarcinoma Antibodies  >3723 publications with EGFR and Adenocarcinoma
 Kidney Diseases Antibodies  >3577 publications with EGFR and Kidney Diseases
 Small Cell Lung Carcinoma Antibodies  >3323 publications with EGFR and Small Cell Lung Carcinoma
 Carcinoma, Non-Small-Cell Lung Antibodies  >3284 publications with EGFR and Carcinoma, Non-Small-Cell Lung
 Disease Progression Antibodies  >2820 publications with EGFR and Disease Progression
 Breast Neoplasms Antibodies  >2558 publications with EGFR and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >2439 publications with EGFR and Carcinoma, Squamous Cell
 Head and Neck Neoplasms Antibodies  >1930 publications with EGFR and Head and Neck Neoplasms

Organs/Tissues associated with anti-EGFR antibody

 Organ/Tissue Name  Pubmed Publications
 Head Antibodies  >1719 publications with EGFR and Head
 Whole Body Antibodies  >65 publications with EGFR and Whole Body
 Fat Body Antibodies  >54 publications with EGFR and Fat Body
 Uncharacterized Tissue Antibodies  >6 publications with EGFR and Uncharacterized Tissue
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