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EIF5A2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5312319

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
EIF5A2, Polyclonal Antibody
Full Product Name
EIF5A2 Antibody
Product Gene Name
anti-EIF5A2 antibody
Product Synonym Names
Affinity Purified Rabbit Polyclonal EIF5A2 Antibody; Polyclonal EIF5A2 antibody; Anti-EIF5A2 antibody; EIF5A2 antibody; EIFA2-5; EIFA2-5 antibody; eukaryotic translation initiation factor 5A2 antibody; eukaryotic translation initiation factor 5A-2 antibody; EIFA2 5 antibody; eukaryotic initiation factor 5A antibody; EIF5A2; EIF-5A2 antibody; eIF-5A-2 antibody; EIFA2 5; eIF5AII antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Purity/Purification
Antigen-Affinity Chromatography
Concentration
0.87 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
17 kDa
OMIM
605782
3D Structure
ModBase 3D Structure for Q9GZV4
Cross-Reactivity
Human

Product Categories/Family for anti-EIF5A2 antibody

DNA & RNA
Applications Tested/Suitable for anti-EIF5A2 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-EIF5A2 antibody
IF: 1:100-1:500
ICC: 1:100-1:500
IHC-P: 1:100-1:500
WB: 1:500-1:3000

Immunofluorescence (IF) of anti-EIF5A2 antibody

Immunofluorescence analysis of methanol-fixed HeLa, using EIF5A2 antibody at 1:200 dilution.
Rabbit Anti-EIF5A2 Polyclonal Antibody – Cat# MBS5312319

Western Blot (WB) of anti-EIF5A2 antibody

Western blot analysis of 30 ug of whole cell lysate (A: 293T; B: A431; C: H1299; D: HeLa S3; E: Hep G2; F: MOLT4; G: Raji) using a 15% SDS PAGE gel and EIF5A2 antibody at a dilution of 1:1000
Rabbit Anti-EIF5A2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS5312319

Immunohistochemistry (IHC) of anti-EIF5A2 antibody

Immunohistochemical staining of paraffin-embedded U87 xenograft using EIF5A2 antibody at a dilution of 1:500
Rabbit Anti-EIF5A2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS5312319

Other Notes

Small volumes of anti-EIF5A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EIF5A2 purchase

MBS5312319 is an antibody targeting EIF5A2. Also known as EIF5A2 Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF5A2. It may not necessarily be applicable to this product.

NCBI GI #
9966867
NCBI GeneID
56648
UniProt Primary Accession #
Q9GZV4
UniProt Related Accession #
Q9GZV4
GenBank Nucleotide #
NP_065123.1
NCBI Official Full Name
eukaryotic translation initiation factor 5A-2
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 5A2
NCBI Official Symbol
EIF5A2
NCBI Official Synonym Symbols
EIF-5A2; eIF5AII
UniProt Protein Name
Eukaryotic translation initiation factor 5A-2
UniProt Synonym Protein Names
Eukaryotic initiation factor 5A isoform 2
UniProt Gene Name
EIF5A2
UniProt Synonym Gene Names
eIF-5A-2; eIF-5A2
UniProt Entry Name
IF5A2_HUMAN
NCBI Protein Information
eukaryotic translation initiation factor 5A-2

UniProt Comments for EIF5A2

EIF5A2: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Belongs to the eIF-5A family.

Chromosomal Location of Human Ortholog: 3q26.2

Cellular Component: endoplasmic reticulum membrane; nuclear pore; cytosol

Molecular Function: protein binding; ribosome binding; translation elongation factor activity

Biological Process: protein transport; mRNA transport; translational frameshifting; cellular protein metabolic process; positive regulation of cell proliferation; positive regulation of translational elongation; spermatogenesis; hypusine biosynthetic process from peptidyl-lysine; polyamine homeostasis; post-translational protein modification; positive regulation of translational termination
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Research Articles on EIF5A2

1. the tumor suppressive role of miR-221-3p in MB cell proliferation at least in part via targeting EIF5A2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EIF5A2 antibody

 Reference Product  PubMed Publications
 DHPS antibody  >2 publications with EIF5A2 and DHPS
 DOHH antibody  >1 publications with EIF5A2 and DOHH

Pathways associated with anti-EIF5A2 antibody

 Products by Pathway  Pathway Diagram
 Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies  Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
 Hypusine Synthesis From EIF5A-lysine Pathway antibodies  Hypusine Synthesis From EIF5A-lysine Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram

Diseases associated with anti-EIF5A2 antibody

 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >5 publications with EIF5A2 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with EIF5A2 and Liver Neoplasms, Experimental
 Skin Diseases Antibodies  >1 publications with EIF5A2 and Skin Diseases
 Disease Models, Animal Antibodies  >1 publications with EIF5A2 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >1 publications with EIF5A2 and Neoplasms, Experimental

Organs/Tissues associated with anti-EIF5A2 antibody

 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >2 publications with EIF5A2 and Stomach
 Lung Antibodies  >2 publications with EIF5A2 and Lung
 Blood Antibodies  >2 publications with EIF5A2 and Blood
 Vascular Antibodies  >2 publications with EIF5A2 and Vascular
 Testis Antibodies  >2 publications with EIF5A2 and Testis
 Brain Antibodies  >2 publications with EIF5A2 and Brain
 Embryonic Tissue Antibodies  >1 publications with EIF5A2 and Embryonic Tissue
 Pancreas Antibodies  >1 publications with EIF5A2 and Pancreas
 Prostate Antibodies  >1 publications with EIF5A2 and Prostate
 Skin Antibodies  >1 publications with EIF5A2 and Skin
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