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GDF15 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5310333

Growth differentiation factor-15 (GDF-15) is disclosed along with its polynucleotide sequence and amino acid sequence. More details

$750 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GDF15, Polyclonal Antibody
Full Product Name
GDF15 antibody (FITC)
Product Gene Name
Product Synonym Names
Rabbit polyclonal GDF15 antibody (FITC); Polyclonal GDF15 antibody; Anti-GDF15 antibody; Growth/differentiation factor 15 antibody; Macrophage inhibitory cytokine 1 antibody; NSAID activated gene 1 protein antibody; NSAID regulated gene 1 protein antibody; Placental TGF beta antibody; Placental bone morphogenetic protein antibody; Prostate differentiation factor antibody; MIC1 antibody; PDF antibody; PLAB antibody; PTGFB antibody; GDF 15 antibody; GDF-15 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied with 0.03% Proclin 300, 50% Glycerol and 0.01M PBS, PH 7.4
Purity/Purification
Purified by Ammonium Sulfate precipitation
Preparation and Storage
Store at 4 degree C for short term storage and-20 degree C for long term storage.
Avoid repeat freeze/thaw cycles.
Molecular Weight
34,140 Da
OMIM
605312
3D Structure
ModBase 3D Structure for Q99988
Immunogen
GDF15 antibody (FITC) was raised in Rabbit using recombinant human Growth/differentiation factor 15 protein as the immunogen
Conjugate
FITC
Cross-Reactivity
Human

Product Categories/Family for anti-GDF15 antibody

Applications Tested/Suitable for anti-GDF15 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

Testing Data of anti-GDF15 antibody

Rabbit Anti-GDF15 Polyclonal Antibody – Cat# MBS5310333

Other Notes

Small volumes of anti-GDF15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDF15 purchase

MBS5310333 is an antibody targeting GDF15. Also known as GDF15 antibody (FITC). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GDF15. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
growth/differentiation factor 15 preproprotein
NCBI Official Synonym Full Names
growth differentiation factor 15
NCBI Official Symbol
GDF15
NCBI Official Synonym Symbols
PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
UniProt Protein Name
Growth/differentiation factor 15
UniProt Synonym Protein Names
Macrophage inhibitory cytokine 1
UniProt Gene Name
GDF15
UniProt Synonym Gene Names
NAG-1; NRG-1
NCBI Protein Information
growth/differentiation factor 15

NCBI Summary for GDF15

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]
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UniProt Comments for GDF15

Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GDF15 antibody

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