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PLCG2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5313612

PLCG2 is a calcium dependent phosphatidylinositol-specific phospholipase C. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate. It is a crucial enzyme in transmembrane signaling. More details

$775 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLCG2, Polyclonal Antibody
Full Product Name
PLCG2 Antibody (Tyr753)
Product Gene Name
Product Synonym Names
Rabbit Polyclonal PLCG2 Antibody (Tyr753); Polyclonal PLCG2 antibody; Anti-PLCG2 antibody; 1-phosphatidylinositol-4 5-bisphosphate phosphodiesterase gamma-2 antibody; Phosphoinositide phospholipase C-gamma-2 antibody; phospholipase C gamma 2 antibody; phospholipase C gamma 2 (phosphatidylinositol-specific) antibody; phospholipase C gamma 2 (phosphatidylyinositol-specific) antibody; Phospholipase C-gamma-2 antibody; Phospholipase C-IV antibody; PLC-gamma-2 antibody; PLC-IV antibody; PLCG-2 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Purity/Purification
Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Specificity
PLCG2 antibody (Tyr753) detects endogenous levels of PLCG2 only when phosphorylated at tyrosine 753
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Immunogen
PLCG2 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human PLCG2 around the phosphorylation site of tyrosine 753 (S-L-YP-D-V) as the immunogen.
Cross-Reactivity
Mouse, Rat

Product Categories/Family for anti-PLCG2 antibody

Applications Tested/Suitable for anti-PLCG2 antibody
Western Blot (WB)
Application Notes for anti-PLCG2 antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-PLCG2 antibody

Western blot analysis of extract from A431 cells, untreated or treated with EGF (200ng/ml, 5min), using PLCgamma2 antibody and PLCG2 antibody (Tyr753) (Lanes 3 and 4)
Rabbit Anti-PLCG2 Polyclonal Antibody – Cat# MBS5313612

Other Notes

Small volumes of anti-PLCG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLCG2 purchase

MBS5313612 is an antibody targeting PLCG2. Also known as PLCG2 Antibody (Tyr753). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLCG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Related Accession #
NCBI Official Full Name
PLCG2 protein
NCBI Official Synonym Full Names
phospholipase C gamma 2
NCBI Official Symbol
PLCG2
NCBI Official Synonym Symbols
FCAS3; APLAID; PLC-IV; PLC-gamma-2
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

NCBI Summary for PLCG2

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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