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SP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS835055

MBS835055 is an antibody targeting SP1. Also known as SP1 antibody. Host: Rabbit. Rabbit polyclonal SP1 antibody More details

$980 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SP1, Polyclonal Antibody
Full Product Name
SP1 antibody
Product Gene Name
anti-SP1 antibody
Product Synonym Names
Polyclonal SP1; Anti-SP1; SP1; SP-1; SP 1
Clonality
Polyclonal
Host
Rabbit
Form/Format
Lyophilized powder. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
3D Structure
ModBase 3D Structure for O890902
Cross-Reactivity
Mouse, Rat, Bovine, Human
Immunogen
SP1 antibody was raised in rabbit using the middle region of SP1 as the immunogen

Product Categories/Family for anti-SP1 antibody

Signal Transduction
Applications Tested/Suitable for anti-SP1 antibody
Western Blot (WB)
Application Notes for anti-SP1 antibody
WB: 1.25 ug/ml

Western Blot of anti-SP1 antibody

Western Blot analysis using SP1 antibody
SP1 antibody used at 0.2-1 ug/ml to detect target protein.
Rabbit Anti-SP1 Polyclonal Antibody – Cat# MBS835055

Other Notes

Small volumes of anti-SP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SP1. It may not necessarily be applicable to this product.

NCBI GI #
1334268
NCBI GeneID
20683
NCBI Accession #
CAA42721.1
UniProt Primary Accession #
O890902
UniProt Related Accession #
O89090
NCBI Official Full Name
Sp1, partial
NCBI Official Synonym Full Names
trans-acting transcription factor 1
NCBI Official Symbol
Sp1
NCBI Official Synonym Symbols
Sp1-1; AA450830; AI845540; 1110003E12Rik
Protein Family
E3 ubiquitin-protein ligase
NCBI Protein Information
transcription factor Sp1

UniProt Comments for SP1

SP1: a transcription factor of the Sp1 C2H2-type zinc-finger protein family. Phosphorylated and activated by MAPK. Dephosphorylation by PTEN inhibits DNA binding. Binds to p38 in the nucleus. Interacts with Huntingtin and TAFII130. Transcriptional activity of SP1 and TAFII130 disrupted in early Huntingtin's Disease.

Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding

Cellular Component: nucleoplasm; cytoplasm; nuclear chromatin; nucleus

Molecular Function: protein C-terminus binding; protein homodimerization activity; histone deacetylase binding; metal ion binding; transcription factor binding; histone acetyltransferase binding; protein binding; nucleic acid binding; DNA binding; sequence-specific DNA binding; double-stranded DNA binding; bHLH transcription factor binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; embryonic placenta development; ossification; transcription, DNA-dependent; in utero embryonic development; megakaryocyte differentiation; embryonic skeletal development; positive regulation of transcription, DNA-dependent; embryonic process involved in female pregnancy; rhythmic process; enucleate erythrocyte differentiation; liver development; trophectodermal cell differentiation; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; embryonic camera-type eye morphogenesis; lung development
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Research Articles on SP1

1. Data suggest that retinoic acid and GM-CSF-induced retinal dehydrogenase 2 (RALDH2) expression in dendritic cells requires cooperative binding of transcription factor Sp1 via the RA receptor/retinoid X receptor complex to the Aldh1a2 promoter.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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