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TrkB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5313728

Brain derived neurotrophic factor (BDNF) and Neurotrophin 4 or 5 are preferred ligands for TrkB. Nevertheless it can also bind to NTF3/neurotrophin-3 that is less efficient in activating the receptor but regulates neuron survival through NTRK2. More details

$775 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TrkB, Polyclonal Antibody
Full Product Name
TrkB Antibody (Tyr705)
Product Gene Name
Product Synonym Names
Rabbit Polyclonal TrkB Antibody (Tyr705); Polyclonal TrkB antibody; Anti-TrkB antibody; Neurotrophic tyrosine kinase receptor type 2 antibody; neurotrophic tyrosine kinase receptor type 2 antibody; NTRK2 antibody; Trk-B antibody; TRKB antibody; TrkB tyrosine kinase antibody; tyrosine kinase receptor B antibody; BDNF-tropomyosine receptor kinase B antibody; BDNF/NT-3 growth factors receptor antibody; GP145-TrkB antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Purity/Purification
Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Specificity
TrkB antibody (Tyr705) detects endogenous levels of TrkB only when phosphorylated at tyrosine 705
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Immunogen
TrkB antibody was raised in Rabbit using a synthesized phosphopeptide derived from human TrkB around the phosphorylation site of tyrosine 705 (T-D-Y P-Y-R) as the immunogen.
Cross-Reactivity
Mouse, Rat

Product Categories/Family for anti-TrkB antibody

Applications Tested/Suitable for anti-TrkB antibody
Western Blot (WB)
Application Notes for anti-TrkB antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-TrkB antibody

Western blot analysis of extracts from mouse brain tissue, using TrkB (Phospho-Tyr705) antibody
Rabbit Anti-TrkB Polyclonal Antibody – Cat# MBS5313728

Other Notes

Small volumes of anti-TrkB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TrkB purchase

MBS5313728 is an antibody targeting TrkB. Also known as TrkB Antibody (Tyr705). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TrkB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Related Accession #
NCBI Official Full Name
trkB
NCBI Official Synonym Full Names
neurotrophic receptor tyrosine kinase 2
NCBI Official Symbol
NTRK2
NCBI Official Synonym Symbols
OBHD; TRKB; trk-B; EIEE58; GP145-TrkB
NCBI Protein Information
BDNF/NT-3 growth factors receptor

NCBI Summary for TrkB

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-TrkB antibody

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