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Cornulin (CRNN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8306372

MBS8306372 is an antibody targeting CRNN. Also known as Anti-Cornulin Antibody. Reactive in Human, Mouse. Host: Rabbit. Rabbit polyclonal antibody to Cornulin More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cornulin (CRNN), Polyclonal Antibody
Full Product Name
Anti-Cornulin Antibody
Product Gene Name
Product Synonym Names
C1orf10; DRC1; PDRC1; SEP53; Cornulin; 53 kDa putative calcium-binding protein; 53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; Squamous epithelial heat shock protein 53; Tumor-related protein
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Specificity
Recognizes endogenous levels of Cornulin protein.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
53,533 Da
OMIM
611312
3D Structure
ModBase 3D Structure for Q9UBG3
Immunogen
Recombinant fusion protein of human Cornulin. The exact sequence is proprietary.
Applications Tested/Suitable for anti-CRNN antibody
Western Blot (WB)
Application Notes for anti-CRNN antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-CRNN antibody

Western blot analysis of Cornulin expression in HEK293T (A), mouse kidney (B) whole cell lysates.
Rabbit Anti-CRNN Polyclonal Antibody – Cat# MBS8306372

Other Notes

Small volumes of anti-CRNN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CRNN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cornulin
NCBI Official Synonym Full Names
cornulin
NCBI Official Symbol
CRNN
NCBI Official Synonym Symbols
DRC1; PDRC1; SEP53; C1orf10
UniProt Protein Name
Cornulin
UniProt Synonym Protein Names
53 kDa putative calcium-binding protein; 53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; Squamous epithelial heat shock protein 53; Tumor-related protein
Protein Family
UniProt Gene Name
CRNN
UniProt Synonym Gene Names
C1orf10; DRC1; PDRC1; SEP53
UniProt Entry Name
CRNN_HUMAN
NCBI Protein Information
cornulin; 53 kDa putative calcium-binding protein; 53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; squamous epithelial heat shock protein 53; tumor-related protein

NCBI Summary for CRNN

This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq, Jan 2009]
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UniProt Comments for CRNN

CRNN: Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest. Belongs to the S100-fused protein family.

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: membrane; cytoplasm

Molecular Function: calcium ion binding

Biological Process: cell-cell adhesion; response to heat
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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