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GPR78 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243757

MBS243757 is an antibody targeting GPR78. Also known as Rabbit Polyclonal to Human GPR78. Reactive in Gorilla, Human. Host: Rabbit. G protein-coupled receptor GPR78 is an Orphan-U GPCR with an unknown ligand. More details

$630 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GPR78, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR78
Product Gene Name
Product Synonym Names
Anti-GPR78 Antibody (C-Terminus) IHC-plus; GPR78; G protein-coupled receptor 78; G-protein coupled receptor 78; Human GPR78
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gorilla, Human
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR78. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
39,332 Da
OMIM
606921
3D Structure
ModBase 3D Structure for Q96P69
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from C-terminus of human GPR78. Percent identity with other species by BLAST analysis: Human, Gorilla (100%).
Immunogen Type
Synthetic peptide
Immunogen
GPR78 antibody was raised against synthetic 19 amino acid peptide from C-terminus of human GPR78. Percent identity with other species by BLAST analysis: Human, Gorilla (100%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-GPR78 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GPR78 antibody
IHC-P (3 - 6 ug/ml)

Immunohistochemistry (IHC) of anti-GPR78 antibody

Anti-GPR78 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR78 Polyclonal Antibody – Cat# MBS243757

Immunohistochemistry (IHC) of anti-GPR78 antibody

Anti-GPR78 antibody IHC of human placenta, villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR78 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243757

Other Notes

Small volumes of anti-GPR78 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR78. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor 78
NCBI Official Synonym Full Names
G protein-coupled receptor 78
NCBI Official Symbol
GPR78
UniProt Protein Name
G-protein coupled receptor 78
UniProt Gene Name
GPR78
UniProt Entry Name
GPR78_HUMAN
NCBI Protein Information
G-protein coupled receptor 78

NCBI Summary for GPR78

The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for GPR78

GPR78: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein signaling, adenylate cyclase activating pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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