• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CK073 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6286256

Required for organization and/or function of the secretory apparatus in Clara cells in lung (By similarity). More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CK073, Polyclonal Antibody
Full Product Name
CK073, NT (C11orf73, Protein Hikeshi) (MaxLight 490)
Product Gene Name
anti-CK073 antibody
Product Synonym Gene Name
C11orf73
Product Synonym Names
C11orf73; Protein Hikeshi
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Hamster, Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
21,628 Da
OMIM
614908
3D Structure
ModBase 3D Structure for Q53FT3
Immunogen
CK073 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human CK073.
Conjugate
MaxLight490
Note
Preservative Free

Product Categories/Family for anti-CK073 antibody

Antibodies; KIAA; orf
Applications Tested/Suitable for anti-CK073 antibody
Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-CK073 antibody
FC/FACS: 1:10-50
FLISA: 1:1,000
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-CK073 antibody

Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009).

Other Notes

Small volumes of anti-CK073 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CK073 purchase

MBS6286256 is an antibody targeting CK073. Also known as CK073, NT (C11orf73, Protein Hikeshi) (MaxLight 490). Reactive in Hamster, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CK073. It may not necessarily be applicable to this product.

NCBI GI #
21361535
NCBI GeneID
51501
NCBI Accession #
NP_057485.2
UniProt Primary Accession #
Q53FT3
UniProt Secondary Accession #
Q8WVE8; Q9NVQ2; Q9NZZ1; Q9P022; Q9P0N1
UniProt Related Accession #
Q53FT3
GenBank Nucleotide #
NM_016401.3
NCBI Official Full Name
protein Hikeshi
NCBI Official Synonym Full Names
chromosome 11 open reading frame 73
NCBI Official Symbol
C11orf73
NCBI Official Synonym Symbols
L7RN6; OPI10; HSPC138; HSPC179; Hikeshi
UniProt Protein Name
Protein Hikeshi
UniProt Gene Name
C11orf73
UniProt Entry Name
HIKES_HUMAN
NCBI Protein Information
protein Hikeshi

UniProt Comments for CK073

C11orf73: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 11q14.2

Cellular Component: intracellular; cell junction; cytosol; nucleus

Molecular Function: Hsp70 protein binding; protein transporter activity

Biological Process: protein transport; protein import into nucleus; Golgi organization and biogenesis; lung development
Show more

Research Articles on CK073

1. identify a nuclear import pathway that operates during heat shock stress and is mediated by an evolutionarily conserved protein, Hikeshi (coded by the C11orf73 gene) binds to FG-Nups and translocates through nuclear pores on its own, showing characteristic features of nuclear transport carriers.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CK073 antibody

 Products by Pathway  Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Regulation Of HSF1-mediated Heat Shock Response Pathway antibodies  Regulation Of HSF1-mediated Heat Shock Response Pathway Diagram
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000