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ABCC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9451678

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1,… More details

$435 / 0.1 mL (Biotin) +1 FREE 8GB USB
Product Documentation
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ABCC2, Polyclonal Antibody
Full Product Name
ABCC2 Conjugated Antibody
Product Gene Name
anti-ABCC2 antibody
Product Synonym Names
DJS; MRP2; cMRP; ABC30; CMOAT
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Specificity
The antibody detects endogenous levels of total ABCC2 protein.
Preparation and Storage
Store at 4 degree C for 6 months.
OMIM
237500
3D Structure
ModBase 3D Structure for Q92887
Immunogen
Synthetic peptide of human ABCC2
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Applications Tested/Suitable for anti-ABCC2 antibody
Most Applications
Application Notes for anti-ABCC2 antibody
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000

Other Notes

Small volumes of anti-ABCC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABCC2 purchase

MBS9451678 is an antibody targeting ABCC2. Also known as ABCC2 Conjugated Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ABCC2. It may not necessarily be applicable to this product.

NCBI GI #
1388169353
NCBI GeneID
1244
NCBI Accession #
NP_000383
UniProt Primary Accession #
Q92887
UniProt Related Accession #
Q92887
GenBank Nucleotide #
NP_000383.2
NCBI Official Full Name
canalicular multispecific organic anion transporter 1
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 2
NCBI Official Symbol
ABCC2
NCBI Official Synonym Symbols
DJS; MRP2; cMRP; ABC30; CMOAT
UniProt Protein Name
Canalicular multispecific organic anion transporter 1
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 2; Canalicular multidrug resistance protein; Multidrug resistance-associated protein 2
Protein Family
ABC transporter C family
UniProt Gene Name
ABCC2
UniProt Synonym Gene Names
CMOAT; CMOAT1; CMRP; MRP2
UniProt Entry Name
MRP2_HUMAN
NCBI Protein Information
canalicular multispecific organic anion transporter 1

UniProt Comments for ABCC2

ABCC2: Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter. Found on the apical membrane of polarized cells in liver, kidney and intestine. The highest expression is found in liver. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.

Protein type: Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: intercellular canaliculus; cell surface; integral to plasma membrane; apical plasma membrane; plasma membrane

Molecular Function: protein domain specific binding; protein binding; ATPase activity, coupled to transmembrane movement of substances; organic anion transmembrane transporter activity; ATP binding

Biological Process: prostaglandin transport; metabolic process; response to heat; response to estrogen stimulus; transport; response to arsenic; multidrug transport; response to methotrexate; response to oxidative stress; cellular chloride ion homeostasis; transmembrane transport

Disease: Dubin-johnson Syndrome
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Research Articles on ABCC2

1. High expression of MRP2 is associated with Hepatocellular Carcinoma and in Cholangiocarcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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