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AKR1CL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8591863

MBS8591863 is an antibody targeting AKR1CL2. Also known as AKR1CL2 Polyclonal Antibody. Reactive in Human. Host: Rabbit. More details

$400 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AKR1CL2, Polyclonal Antibody
Full Product Name
AKR1CL2 Polyclonal Antibody
Product Gene Name
Product Synonym Names
AKR1E2; AKR1CL2; AKRDC1; 1; 5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; LoopADR; Testis-specific protein; hTSP
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
AKR1CL2 Polyclonal Antibody detects endogenous levels of AKR1CL2 protein.
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
Molecular Weight
36,589 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (4868369..4890254). Location: 10p15.1
3D Structure
ModBase 3D Structure for Q96JD6
Immunogen
Synthesized peptide derived from the Internal region of human AKR1CL2.

Product Categories/Family for anti-AKR1CL2 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-AKR1CL2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-AKR1CL2 antibody
WB: 1:500-1:2000
IHC: 1:100-1:300
ELISA: 1:10000

Other Notes

Small volumes of anti-AKR1CL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AKR1CL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
1,5-anhydro-D-fructose reductase isoform 1
NCBI Official Synonym Full Names
aldo-keto reductase family 1, member E2
NCBI Official Symbol
AKR1E2
NCBI Official Synonym Symbols
hTSP; htAKR; AKRDC1; AKR1CL2; LoopADR
UniProt Protein Name
1,5-anhydro-D-fructose reductase
UniProt Synonym Protein Names
Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; LoopADR; Testis-specific protein
UniProt Gene Name
AKR1E2
UniProt Synonym Gene Names
AKR1CL2; AKRDC1; AF reductase; hTSP
UniProt Entry Name
AKCL2_HUMAN
NCBI Protein Information
1,5-anhydro-D-fructose reductase; AF reductase; testis-specific protein; aldo-keto reductase loopADR; aldo-keto reductase family 1, member C-like 2; aldo-keto reductase family 1 member C-like protein 2

NCBI Summary for AKR1CL2

The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
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UniProt Comments for AKR1CL2

AKR1CL2: Catalyzes the NADPH-dependent reduction of 1,5-anhydro- D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones. Has low NADPH-dependent reductase activity towards 9,10- phenanthrenequinone (in vitro). Belongs to the aldo/keto reductase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.1.1.263

Chromosomal Location of Human Ortholog: 10p15.1

Cellular Component: cytoplasm

Molecular Function: 1,5-anhydro-D-fructose reductase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-AKR1CL2 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with AKR1CL2 and Eye
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