ALDH9A1 Antibody – Rabbit Polyclonal

This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]

ALDH9A1: Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Belongs to the aldehyde dehydrogenase family.

Protein type: Carbohydrate Metabolism - propanoate; EC 1.2.1.47; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Lipid Metabolism - glycerolipid; Oxidoreductase; Lipid Metabolism - fatty acid; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - butanoate; EC 1.2.1.3; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - tryptophan; Mitochondrial; Secondary Metabolites Metabolism - limonene and pinene degradation; Other Amino Acids Metabolism - beta-alanine; Carbohydrate Metabolism - ascorbate and aldarate

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: mitochondrion; cytoplasm; cytosol

Molecular Function: 1-pyrroline dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; amine binding; protein homodimerization activity; aminobutyraldehyde dehydrogenase activity; 3-chloroallyl aldehyde dehydrogenase activity; 4-trimethylammoniobutyraldehyde dehydrogenase activity; NAD binding

Biological Process: hormone metabolic process; aldehyde metabolic process; kidney development; liver development; carnitine biosynthetic process; neurotransmitter biosynthetic process