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AMOTL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9417047

The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to… More details

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Product Overview

Online Datasheet in PDF
Product Name
AMOTL1, Polyclonal Antibody
Full Product Name
AMOTL1 Antibody
Product Gene Name
Product Synonym Names
JEAP
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Purity/Purification
Antigen affinity purification
Concentration
1.4mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total AMOTL1 protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
101,179 Da
OMIM
AK074084 mRNA
3D Structure
ModBase 3D Structure for Q8IY63
Immunogen
Synthetic peptide of human AMOTL1
Immunogen Type
Peptide

Product Categories/Family for anti-AMOTL1 antibody

Applications Tested/Suitable for anti-AMOTL1 antibody
Western Blot (WB)
Application Notes for anti-AMOTL1 antibody
Western Blot: 1:200-1000

SDS-Page of anti-AMOTL1 antibody

Gel: 6%SDS-PAGE Lysate: 40 ug, Lane: A172 cell lysate, Primary antibody:AMOTL1 antibody at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
Rabbit Anti-AMOTL1 Polyclonal Antibody – Cat# MBS9417047

Other Notes

Small volumes of anti-AMOTL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMOTL1 purchase

MBS9417047 is an antibody targeting AMOTL1. Also known as AMOTL1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AMOTL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
angiomotin-like protein 1 isoform 2
NCBI Official Synonym Full Names
angiomotin like 1
NCBI Official Symbol
AMOTL1
NCBI Official Synonym Symbols
JEAP
UniProt Protein Name
Angiomotin-like protein 1
UniProt Gene Name
AMOTL1
UniProt Entry Name
AMOL1_HUMAN
NCBI Protein Information
angiomotin-like protein 1

UniProt Comments for AMOTL1

AMOTL1: Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Belongs to the angiomotin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 11q14.3

Cellular Component: cell junction; cytoplasm; cytosol; signalosome; tight junction

Molecular Function: identical protein binding; protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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