Rabbit Anti-APPBP2 Polyclonal Antibody – Cat# MBS646787

APPBP2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the APPBP2 antibody detected the APPBP2 protein (arrow).

APPBP2 Antibody – Rabbit Polyclonal

Name: APPBP2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646787
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646787

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

APPBP2, Polyclonal Antibody

Full Product Name

APPBP2, ID (APPBP2, KIAA0228, PAT1, Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, Protein interacting with APP tail 1)

Product Gene Name

anti-APPBP2 antibody

Product Synonym Names

Anti -APPBP2, ID (APPBP2, KIAA0228, PAT1, Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, Protein interacting with APP tail 1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

66,853 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (58520520..58603580, complement). Location: 17q23.2

OMIM

605324

3D Structure

ModBase 3D Structure for Q92624

Immunogen

APPBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-271 amino acids from the Central region of human APPBP2.

Product Categories/Family for anti-APPBP2 antibody

Antibodies; Abs to Amyloid

Applications Tested/Suitable for anti-APPBP2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-APPBP2 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-APPBP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APPBP2 purchase

MBS646787 is an antibody targeting APPBP2. Also known as APPBP2, ID (APPBP2, KIAA0228, PAT1, Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, Protein interacting with APP tail 1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for APPBP2. It may not necessarily be applicable to this product.

NCBI GI #

541862246

NCBI GeneID

10513

NCBI Accession #

NP_001269405.1

UniProt Primary Accession #

Q92624

UniProt Secondary Accession #

O95095; Q8WVC9; A8K862

UniProt Related Accession #

Q92624

GenBank Nucleotide #

NM_001282476.1

NCBI Official Full Name

amyloid protein-binding protein 2 isoform 2

NCBI Official Synonym Full Names

amyloid beta precursor protein (cytoplasmic tail) binding protein 2

NCBI Official Symbol

APPBP2

NCBI Official Synonym Symbols

PAT1; APP-BP2; HS.84084

UniProt Protein Name

Amyloid protein-binding protein 2

UniProt Synonym Protein Names

Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1

Protein Family

Amyloid protein-binding protein

UniProt Gene Name

APPBP2

UniProt Synonym Gene Names

KIAA0228; PAT1; APP-BP2

UniProt Entry Name

APBP2_HUMAN

NCBI Protein Information

amyloid protein-binding protein 2; protein interacting with APP tail 1

NCBI Summary for APPBP2

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

UniProt Comments for APPBP2

Function: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface. Ref.1

Subunit structure: Binds APP.

Subcellular location: Nucleus. Cytoplasm › cytoskeleton. Membrane; Peripheral membrane protein

Potential. Note: Associated with membranes and microtubules. Ref.1 Ref.6

Post-translational modification: Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.

Sequence similarities: Contains 8 TPR repeats.

Sequence caution: The sequence BAA13217.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on APPBP2

1. Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-APPBP2 antibody

Reference Product	PubMed Publications
RPS6KB1 antibody	>3 publications with APPBP2 and RPS6KB1
PPM1D antibody	>3 publications with APPBP2 and PPM1D

Pathways associated with anti-APPBP2 antibody

Products by Pathway	Pathway Diagram
Regulation Of Androgen Receptor Activity Pathway antibodies	Regulation Of Androgen Receptor Activity Pathway Diagram

Diseases associated with anti-APPBP2 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>6 publications with APPBP2 and Neoplasms
Skin Diseases Antibodies	>2 publications with APPBP2 and Skin Diseases
Breast Neoplasms Antibodies	>2 publications with APPBP2 and Breast Neoplasms
Nervous System Diseases Antibodies	>1 publications with APPBP2 and Nervous System Diseases
Adenocarcinoma Antibodies	>1 publications with APPBP2 and Adenocarcinoma
Infertility, Male Antibodies	>1 publications with APPBP2 and Infertility, Male
Ovarian Diseases Antibodies	>1 publications with APPBP2 and Ovarian Diseases
Infertility, Female Antibodies	>1 publications with APPBP2 and Infertility, Female

Organs/Tissues associated with anti-APPBP2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1 publications with APPBP2 and Blood
Prostate Antibodies	>1 publications with APPBP2 and Prostate
Uncharacterized Tissue Antibodies	>1 publications with APPBP2 and Uncharacterized Tissue
Testis Antibodies	>1 publications with APPBP2 and Testis