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AQP5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6274657

Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AQP5, Polyclonal Antibody
Full Product Name
AQP5, CT (AQP5, Aquaporin-5) (FITC)
Product Gene Name
Product Synonym Names
AQP5; Aquaporin-5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human AQP5.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
28,292 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (50355279..50359461). Location: 12q13
OMIM
600442
3D Structure
ModBase 3D Structure for P55064
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 227-256 in the C-terminal region of human AQP5, UniProt Accession #P55064.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-AQP5 antibody

Applications Tested/Suitable for anti-AQP5 antibody
Western Blot (WB), FLISA
Application Notes for anti-AQP5 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-AQP5 antibody

Western blot analysis of NCI-H292 cell line lysates (35ug/lane) usingMBS649455. This demonstrates the AQP5 antibody detected the AQP5 protein (arrow).
Rabbit Anti-AQP5 Polyclonal Antibody – Cat# MBS6274657

Product References and Citations for anti-AQP5 antibody

Shen, Y., et al. Respir Physiol Neurobiol 171(3):212-217(2010). Shen, L., et al. Biomed. Pharmacother. 64(5):313-318(2010). Shankardas, J., et al. Mol. Vis. 16, 1538-1548 (2010): Dimasi, D.P., et al. Mol. Vis. 16, 562-569 (2010): Nejsum, L.N., et al. Proc. Natl. Acad. Sci. U.S.A. 99(1):511-516(2002).

Other Notes

Small volumes of anti-AQP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AQP5 purchase

MBS6274657 is an antibody targeting AQP5. Also known as AQP5, CT (AQP5, Aquaporin-5) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AQP5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
aquaporin-5
NCBI Official Synonym Full Names
aquaporin 5
NCBI Official Symbol
AQP5
NCBI Official Synonym Symbols
AQP-5
UniProt Protein Name
Aquaporin-5
Protein Family
UniProt Gene Name
AQP5
UniProt Synonym Gene Names
AQP-5
UniProt Entry Name
AQP5_HUMAN
NCBI Protein Information
aquaporin-5

UniProt Comments for AQP5

AQP5: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, aquaporin family; Membrane protein, integral; Channel, misc.

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: microvillus; endoplasmic reticulum; integral to plasma membrane; apical plasma membrane; plasma membrane; basal plasma membrane

Molecular Function: protein binding; water channel activity; glycerol channel activity

Biological Process: odontogenesis; glycerol transport; cellular water homeostasis; camera-type eye morphogenesis; water transport; carbon dioxide transport; excretion; pancreatic juice secretion; transmembrane transport; saliva secretion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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