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ARAP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6274696

The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ARAP2, Polyclonal Antibody
Full Product Name
ARAP2, NT (ARAP2, CENTD1, KIAA0580, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, Centaurin-delta-1, Protein PARX) (MaxLight 750)
Product Gene Name
Product Synonym Names
ARAP2; CENTD1; KIAA0580; Arf-GAP with Rho-GAP domain; ANK repeat and PH domain-containing protein 2; Centaurin-delta-1; Protein PARX
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
193,452 Da
3D Structure
ModBase 3D Structure for Q8WZ64
Immunogen
ARAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-93 amino acids from the N-terminal region of human ARAP2.
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-ARAP2 antibody

Applications Tested/Suitable for anti-ARAP2 antibody
Western Blot (WB), FLISA
Application Notes for anti-ARAP2 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-ARAP2 antibody

Gavicherla, B., et al. Infect. Immun. 78(11):4532-4541(2010). Liu, C., et al. Mol. Med. 14 (9-10), 575-581 (2008): Yoon, H.Y., et al. J. Cell. Sci. 119 (PT 22), 4650-4666 (2006): Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006).

Other Notes

Small volumes of anti-ARAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARAP2 purchase

MBS6274696 is an antibody targeting ARAP2. Also known as ARAP2, NT (ARAP2, CENTD1, KIAA0580, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, Centaurin-delta-1, Protein PARX) (MaxLight 750). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARAP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
NCBI Official Synonym Full Names
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
NCBI Official Symbol
ARAP2
NCBI Official Synonym Symbols
PARX; CENTD1
UniProt Protein Name
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
UniProt Synonym Protein Names
Centaurin-delta-1; Cnt-d1; Protein PARX
UniProt Gene Name
ARAP2
UniProt Synonym Gene Names
CENTD1; KIAA0580; Cnt-d1
NCBI Protein Information
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2; cnt-d1; centaurin-delta-1; centaurin, delta 1; Arf and Rho GAP adapter protein 2

UniProt Comments for ARAP2

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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