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ARHGAP12 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647639

MBS647639 is an antibody targeting ARHGAP12. Also known as ARHGAP12 (Rho GTPase-activating Protein 12, Rho-type GTPase-activating Protein 12, DKFZp779N2050, FLJ10971, FLJ20737, FLJ21785, FLJ45709). Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARHGAP12, Polyclonal Antibody
Full Product Name
ARHGAP12 (Rho GTPase-activating Protein 12, Rho-type GTPase-activating Protein 12, DKFZp779N2050, FLJ10971, FLJ20737, FLJ21785, FLJ45709)
Product Gene Name
anti-ARHGAP12 antibody
Product Synonym Names
Anti -ARHGAP12 (Rho GTPase-activating Protein 12, Rho-type GTPase-activating Protein 12, DKFZp779N2050, FLJ10971, FLJ20737, FLJ21785, FLJ45709)
Immunogen Sequence
MKMADRSGKI IPGQVYIEVE YDYEYEAKDR KIVIKQGERY ILVKKTNDDW WQVKPDENSK AFYVPAQYVK EVTRKALMPP VKQVAGLPNN STKIMQSLHL QRSTENVNKL PELSSFGKPS SSVQGTGLIR DANQNFGPSY NQGQTVNLSL DLTHNNGKFN NDSHSPKVSS QNRTRSFGHF PGPEFLDVEK TSFSQEQSCD SAGEGSERIH QDSESGDELS SSSTEQIRAT TPPNQGRPDS PVYANLQELK ISQSALPPLP GSPAIQINGE WETHKDSSGR CYYYNRGTQE RTWKPPRWTR DASISKGDFQ NPGDQELLSS EENYYSTSYS QSDSQCGSPP RGWSEELDER GHTLYTSDYT NEKWLKHVDD QGRQYYYSAD GSRSEWELPK YNASSQQQRE IIKSRSLDRR LQEPIVLTKW RHSTIVLDTN DKESPTASKP CFPENESSPS SPKHQDTDQE KYGLLNVTKI AENGKKVRKN WLSSWAVLQG SSLLFTKTQG SSTSWFGSNQ SKPEFTVDLK GATIEMASKD KSSKKNVFEL KTRQGTELLI QSDNDTVIND WFKVLSSTIN NQAVETDEGI EEEIPDSPGI EKHDKEKEQK DPKKLRSFKV SSIDSSEQKK TKKNLKKFLT RRPTLQAVRE KGYIKDQVFG SNLANLCQRE NGTVPKFVKL CIEHVEEHGL DIDGIYRVSG NLAVIQKLRF AVNHDEKLDL NDSKWEDIHV ITGALKMFFR ELPEPLFTFN HFNDFVNAIK QEPRQRVAAV KDLIRQLPKP NQDTMQILFR HLRRVIENGE KNRMTYQSIA IVFGPTLLKP EKETGNIAVH TVYQNQIVEL ILLELSSIFG R
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human ARHGAP12.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
96,254 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (32094326..32217804, complement). Location: 10p11.22
OMIM
610577
3D Structure
ModBase 3D Structure for Q8IWW6
Immunogen
Full length human ARHGAP12, aa1-841 (AAH94719.1).

Product Categories/Family for anti-ARHGAP12 antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins
Applications Tested/Suitable for anti-ARHGAP12 antibody
Western Blot (WB)
Application Notes for anti-ARHGAP12 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-ARHGAP12 antibody

Western Blot analysis of ARHGAP12 expression in transfected 293T cell line by ARHGAP12 polyclonal antibody. Lane 1: ARHGAP12 transfected lysate (92.51kD). Lane 2: Non-transfected lysate.
Mouse Anti-ARHGAP12 Polyclonal Antibody – Cat# MBS647639

Other Notes

Small volumes of anti-ARHGAP12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP12. It may not necessarily be applicable to this product.

NCBI GI #
92098111
NCBI GeneID
94134
NCBI Accession #
AAI15364.1
UniProt Primary Accession #
Q8IWW6
UniProt Secondary Accession #
Q504X1; Q86UB3; Q8IWW7; Q8N3L1; Q9NT76; B1ANY0; B1ANY1; B1ANY2
UniProt Related Accession #
Q8IWW6
NCBI Official Full Name
ARHGAP12 protein
NCBI Official Synonym Full Names
Rho GTPase activating protein 12
NCBI Official Symbol
ARHGAP12
UniProt Protein Name
Rho GTPase-activating protein 12
UniProt Synonym Protein Names
Rho-type GTPase-activating protein 12
Protein Family
Rho GTPase-activating protein
UniProt Gene Name
ARHGAP12
UniProt Entry Name
RHG12_HUMAN
NCBI Protein Information
rho GTPase-activating protein 12; rho-type GTPase-activating protein 12

NCBI Summary for ARHGAP12

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
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UniProt Comments for ARHGAP12

Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state

By similarity.

Sequence similarities: Contains 1 PH domain.Contains 1 Rho-GAP domain.Contains 1 SH3 domain.Contains 2 WW domains.

Research Articles on ARHGAP12

1. molecular cloning and characterization of ARHGAP12

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ARHGAP12 antibody

 Products by Pathway  Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram

Diseases associated with anti-ARHGAP12 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with ARHGAP12 and Neoplasms

Organs/Tissues associated with anti-ARHGAP12 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with ARHGAP12 and Blood
 Lung Antibodies  >1 publications with ARHGAP12 and Lung
 Kidney Antibodies  >1 publications with ARHGAP12 and Kidney
 Bladder Antibodies  >1 publications with ARHGAP12 and Bladder
 Brain Antibodies  >1 publications with ARHGAP12 and Brain
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