Rabbit Anti-ARHGEF6 Polyclonal Antibody – Cat# MBS6275043

ARHGEF6 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ARHGEF6 antibody detected the ARHGEF6 protein (arrow).

ARHGEF6 Antibody – Rabbit Polyclonal

Name: ARHGEF6 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6275043
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6275043

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ARHGEF6, Polyclonal Antibody

Full Product Name

ARHGEF6, CT (ARHGEF6, COOL2, KIAA0006, PIXA, Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6) (Azide free) (HRP)

Product Gene Name

anti-ARHGEF6 antibody

Product Synonym Names

ARHGEF6; COOL2; KIAA0006; PIXA; Rho guanine nucleotide exchange factor 6; Alpha-Pix; COOL-2; PAK-interacting exchange factor alpha; Rac/Cdc42 guanine nucleotide exchange factor 6

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

87,499 Da

Chromosome Location

Chromosome: X; NC_000023.11 (136665549..136781344, complement). Location: Xq26.3

OMIM

300267

3D Structure

ModBase 3D Structure for Q15052

Immunogen

ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human ARHGEF6.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-ARHGEF6 antibody

Antibodies; Cell Division Cycle (CDC)

Applications Tested/Suitable for anti-ARHGEF6 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-ARHGEF6 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-ARHGEF6 antibody

Maiti, A.K. Pharmacogenomics J. 10(2):94-104(2010). Eriguchi, M., et al. J. Neurol. Sci. 290 (1-2), 80-85 (2010): Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010). Lim, J.W., et al. Scand. J. Gastroenterol. 44(10):1166-1172(2009). Baek, H.Y., et al. Ann. N. Y. Acad. Sci. 1096, 18-23 (2007).

Other Notes

Small volumes of anti-ARHGEF6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARHGEF6 purchase

MBS6275043 is an antibody targeting ARHGEF6. Also known as ARHGEF6, CT (ARHGEF6, COOL2, KIAA0006, PIXA, Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGEF6. It may not necessarily be applicable to this product.

NCBI GI #

22027525

NCBI GeneID

9459

NCBI Accession #

NP_004831.1

UniProt Primary Accession #

Q15052

UniProt Secondary Accession #

Q15396; Q5JQ66; Q7Z3W1; Q86XH0; A6NMW9; A8K6S7; B1AL37

UniProt Related Accession #

Q15052

GenBank Nucleotide #

NM_004840.2

NCBI Official Full Name

rho guanine nucleotide exchange factor 6

NCBI Official Synonym Full Names

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

NCBI Official Symbol

ARHGEF6

NCBI Official Synonym Symbols

PIXA; COOL2; MRX46; Cool-2; alphaPIX; alpha-PIX

UniProt Protein Name

Rho guanine nucleotide exchange factor 6

UniProt Synonym Protein Names

Alpha-Pix; COOL-2; PAK-interacting exchange factor alpha; Rac/Cdc42 guanine nucleotide exchange factor 6

Protein Family

Rho guanine nucleotide exchange factor

UniProt Gene Name

ARHGEF6

UniProt Synonym Gene Names

COOL2; KIAA0006; PIXA

UniProt Entry Name

ARHG6_HUMAN

NCBI Protein Information

rho guanine nucleotide exchange factor 6; PAK-interacting exchange factor alpha; PAK-interacting exchange factor, alpha; Rac/Cdc42 guanine exchange factor (GEF) 6; rac/Cdc42 guanine nucleotide exchange factor 6

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ARHGEF6 antibody

Reference Product	PubMed Publications
PAK3 antibody	>11 publications with ARHGEF6 and PAK3
CDC42 antibody	>10 publications with ARHGEF6 and CDC42
OPHN1 antibody	>9 publications with ARHGEF6 and OPHN1
RAC1 antibody	>6 publications with ARHGEF6 and RAC1
ILK antibody	>3 publications with ARHGEF6 and ILK
GIT1 antibody	>1 publications with ARHGEF6 and GIT1
PARVB antibody	>1 publications with ARHGEF6 and PARVB

Pathways associated with anti-ARHGEF6 antibody

Products by Pathway	Pathway Diagram
CDC42 Signaling Events Pathway antibodies	CDC42 Signaling Events Pathway Diagram
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies	Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
Cell Junction Organization Pathway antibodies	Cell Junction Organization Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Cell-extracellular Matrix Interactions Pathway antibodies	Cell-extracellular Matrix Interactions Pathway Diagram
Class I PI3K Signaling Events Pathway antibodies	Class I PI3K Signaling Events Pathway Diagram
G Alpha (12/13) Signalling Events Pathway antibodies	G Alpha (12/13) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
NRAGE Signals Death Through JNK Pathway antibodies	NRAGE Signals Death Through JNK Pathway Diagram
Pancreatic Cancer Pathway antibodies	Pancreatic Cancer Pathway Diagram

Diseases associated with anti-ARHGEF6 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with ARHGEF6 and Neoplasms
Cognition Disorders Antibodies	>2 publications with ARHGEF6 and Cognition Disorders
Ataxia Antibodies	>1 publications with ARHGEF6 and Ataxia
Disease Models, Animal Antibodies	>1 publications with ARHGEF6 and Disease Models, Animal
Heart Diseases Antibodies	>1 publications with ARHGEF6 and Heart Diseases
Learning Disorders Antibodies	>1 publications with ARHGEF6 and Learning Disorders
Lymphoma Antibodies	>1 publications with ARHGEF6 and Lymphoma
Necrosis Antibodies	>1 publications with ARHGEF6 and Necrosis
Mental Retardation, X-Linked 46 Antibodies	>1 publications with ARHGEF6 and Mental Retardation, X-Linked 46

Organs/Tissues associated with anti-ARHGEF6 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>8 publications with ARHGEF6 and Brain
Testis Antibodies	>2 publications with ARHGEF6 and Testis
Blood Antibodies	>2 publications with ARHGEF6 and Blood
Lung Antibodies	>1 publications with ARHGEF6 and Lung
Heart Antibodies	>1 publications with ARHGEF6 and Heart