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ARPC3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6464093

MBS6464093 is an antibody targeting ARPC3. Also known as ARPC3, CT (Actin-related Protein 2/3 Complex Subunit 3, Arp2/3 Complex 21kD Subunit, p21-ARC, ARC21) (MaxLight 405). Reactive in Human. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARPC3, Polyclonal Antibody
Full Product Name
ARPC3, CT (Actin-related Protein 2/3 Complex Subunit 3, Arp2/3 Complex 21kD Subunit, p21-ARC, ARC21) (MaxLight 405)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human ARPC3.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
22.9 kDa (201aa) confirmed by MALDI-TOF
OMIM
604225
3D Structure
ModBase 3D Structure for O15145
Immunogen
Synthetic peptide selected from the C-terminal region of human ARPC3 (KLH).
Conjugate
MaxLight405
Note
Preservative Free
Applications Tested/Suitable for anti-ARPC3 antibody
Western Blot (WB), FLISA
Application Notes for anti-ARPC3 antibody
WB: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ARPC3 antibody

Western blot analysis of ARPC3 antibody (C-term) in HL60 cell line lysates(35ug/lane). ARPC3 (arrow) was detected using the purified Pab.
Rabbit Anti-ARPC3 Polyclonal Antibody – Cat# MBS6464093

Immunohistochemistry (IHC) of anti-ARPC3 antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with ARPC3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-ARPC3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6464093

Product References and Citations for anti-ARPC3 antibody

1. Dubois, T., Nat. Cell Biol. 7(4), 353-364 (2005).

Other Notes

Small volumes of anti-ARPC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARPC3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Synonym Full Names
actin related protein 2/3 complex subunit 3
NCBI Official Symbol
ARPC3
NCBI Official Synonym Symbols
ARC21; p21-Arc
UniProt Protein Name
Actin-related protein 2/3 complex subunit 3
UniProt Synonym Protein Names
Arp2/3 complex 21 kDa subunit; p21-ARC
UniProt Gene Name
ARPC3
UniProt Synonym Gene Names
ARC21; p21-ARC
UniProt Entry Name
ARPC3_HUMAN
NCBI Protein Information
actin-related protein 2/3 complex subunit 3

NCBI Summary for ARPC3

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
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UniProt Comments for ARPC3

ARPC3: one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12q24.11

Cellular Component: Arp2/3 protein complex; focal adhesion; membrane; lamellipodium; cytosol; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton

Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ARPC3 antibody

 Disease Name  Pubmed Publications
 Embryo Loss Antibodies  >1 publications with ARPC3 and Embryo Loss
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