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ASZ1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7001473

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements… More details

$230 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASZ1, Polyclonal Antibody
Full Product Name
ASZ1 Antibody; Biotin conjugated
Product Gene Name
anti-ASZ1 antibody
Product Synonym Names
Ankyrin repeat; SAM and basic leucine zipper domain-containing protein 1; Ankyrin-like protein 1; Germ cell-specific ankyrin; SAM and basic leucine zipper domain-containing protein; ASZ1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%,Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
Matching Pairs
Unconjugated Antibody: ASZ1 (MBS7006833)
Biotin Conjugated Antibody: ASZ1 (MBS7001473)
Molecular Weight
52,432 Da
OMIM
605797
3D Structure
ModBase 3D Structure for Q8WWH4
Immunogen
Recombinant human Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein
Conjugation
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-79854 / sc-79852
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ASZ1 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-ASZ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASZ1 purchase

MBS7001473 is an antibody targeting ASZ1. Also known as ASZ1 Antibody; Biotin conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASZ1. It may not necessarily be applicable to this product.

NCBI GI #
685844859
NCBI GeneID
136991
NCBI Accession #
NP_001288750.1
UniProt Primary Accession #
Q8WWH4
UniProt Secondary Accession #
A0AV27; A4D0V0; B7ZM20
UniProt Related Accession #
Q8WWH4
GenBank Nucleotide #
NM_001301821.1
NCBI Official Full Name
ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 isoform 2
NCBI Official Synonym Full Names
ankyrin repeat, SAM and basic leucine zipper domain containing 1
NCBI Official Symbol
ASZ1
NCBI Official Synonym Symbols
ALP1; GASZ; Orf3; ANKL1; C7orf7; CT1.19
UniProt Protein Name
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
UniProt Synonym Protein Names
Ankyrin-like protein 1; Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein
Protein Family
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein
UniProt Gene Name
ASZ1
UniProt Entry Name
ASZ1_HUMAN
NCBI Protein Information
ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

UniProt Comments for ASZ1

ASZ1: Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7q31.2

Cellular Component: cytoplasm

Molecular Function: signal transducer activity

Biological Process: cell differentiation; DNA methylation during gametogenesis; gene expression; male meiosis; multicellular organismal development; RNA-mediated gene silencing; signal transduction; spermatogenesis
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Research Articles on ASZ1

1. Data reveal a potential role of GASZ during embryonic germ cell development and provide a powerful in vitro system for dissecting the molecular pathways in early germ cell formation during embryogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ASZ1 antibody

 Reference Product  PubMed Publications
 DAZL antibody  >1 publications with ASZ1 and DAZL

Pathways associated with anti-ASZ1 antibody

 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Gene Silencing By RNA Pathway antibodies  Gene Silencing By RNA Pathway Diagram
 PIWI-interacting RNA (piRNA) Biogenesis Pathway antibodies  PIWI-interacting RNA (piRNA) Biogenesis Pathway Diagram

Diseases associated with anti-ASZ1 antibody

 Disease Name  Pubmed Publications
 Infertility, Female Antibodies  >1 publications with ASZ1 and Infertility, Female
 Respiratory Tract Diseases Antibodies  >1 publications with ASZ1 and Respiratory Tract Diseases
 Infertility, Male Antibodies  >1 publications with ASZ1 and Infertility, Male

Organs/Tissues associated with anti-ASZ1 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >2 publications with ASZ1 and Testis
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