Rabbit Anti-ATP1A3 Polyclonal Antibody – Cat# MBS6276396

ATP1A3 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ATP1A3 antibody detected the ATP1A3 protein (arrow).

ATP1A3 Antibody – Rabbit Polyclonal

Name: ATP1A3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6276396
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6276396

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ATP1A3, Polyclonal Antibody

Full Product Name

ATP1A3, ID (ATP1A3, Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3) (Azide free) (HRP)

Product Gene Name

anti-ATP1A3 antibody

Product Synonym Names

ATP1A3; Sodium/potassium-transporting ATPase subunit alpha-3; Na(+)/K(+) ATPase alpha(III) subunit; Sodium pump subunit alpha-3

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

111 kDa

OMIM

gene 614820

3D Structure

ModBase 3D Structure for P13637

Immunogen

ATP1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-833 amino acids from the Central region of human ATP1A3.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-ATP1A3 antibody

Antibodies; Ion Channel

Applications Tested/Suitable for anti-ATP1A3 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-ATP1A3 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-ATP1A3 antibody

Einholm, A.P., et al. J. Biol. Chem. 285(34):26245-26254(2010). Floyd, R.V., et al. Reprod Sci 17(4):366-376(2010). Hauck, C., et al. Eur. J. Pharmacol. 622 (1-3), 7-14 (2009): Blanco-Arias, P., et al. Hum. Mol. Genet. 18(13):2370-2377(2009). Goldstein, I., et al. Biol. Psychiatry 65(11):985-991(2009).

Other Notes

Small volumes of anti-ATP1A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATP1A3 purchase

MBS6276396 is an antibody targeting ATP1A3. Also known as ATP1A3, ID (ATP1A3, Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP1A3. It may not necessarily be applicable to this product.

NCBI GI #

22748667

NCBI GeneID

478

NCBI Accession #

NP_689509.1

UniProt Primary Accession #

P13637

UniProt Related Accession #

P13637

GenBank Nucleotide #

NM_152296.5

NCBI Official Full Name

sodium/potassium-transporting ATPase subunit alpha-3 isoform 1

NCBI Official Synonym Full Names

ATPase Na+/K+ transporting subunit alpha 3

NCBI Official Symbol

ATP1A3

NCBI Official Synonym Symbols

RDP; AHC2; CAPOS; DYT12; ATP1A1

UniProt Protein Name

Sodium/potassium-transporting ATPase subunit alpha-3

UniProt Synonym Protein Names

Na(+)/K(+) ATPase alpha(III) subunit; Sodium pump subunit alpha-3

Protein Family

Sodium/potassium-transporting ATPase

UniProt Gene Name

ATP1A3

UniProt Synonym Gene Names

Na(+)/K(+) ATPase alpha-3 subunit

UniProt Entry Name

AT1A3_HUMAN

NCBI Protein Information

sodium/potassium-transporting ATPase subunit alpha-3

NCBI Summary for ATP1A3

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Research Articles on ATP1A3

1. sequencing analysis of ATP1A3 gene was performed, showing a trinucleotide deletion c.2266_2268delGAC p.(D756del) (NM_001256214).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ATP1A3 antibody

Reference Product	PubMed Publications
ATP1A1 antibody	>28 publications with ATP1A3 and ATP1A1
ATP1B1 antibody	>6 publications with ATP1A3 and ATP1B1
ATP1B3 antibody	>4 publications with ATP1A3 and ATP1B3
ATP1B2 antibody	>3 publications with ATP1A3 and ATP1B2
ATP1A4 antibody	>2 publications with ATP1A3 and ATP1A4
UBC antibody	>1 publications with ATP1A3 and UBC

Pathways associated with anti-ATP1A3 antibody

Products by Pathway	Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Aldosterone-regulated Sodium Reabsorption Pathway antibodies	Aldosterone-regulated Sodium Reabsorption Pathway Diagram
Aldosterone-regulated Sodium Reabsorption Pathway antibodies	Aldosterone-regulated Sodium Reabsorption Pathway Diagram
Bile Secretion Pathway antibodies	Bile Secretion Pathway Diagram
Bile Secretion Pathway antibodies	Bile Secretion Pathway Diagram
Carbohydrate Digestion And Absorption Pathway antibodies	Carbohydrate Digestion And Absorption Pathway Diagram
Carbohydrate Digestion And Absorption Pathway antibodies	Carbohydrate Digestion And Absorption Pathway Diagram
Cardiac Conduction Pathway antibodies	Cardiac Conduction Pathway Diagram
Cardiac Muscle Contraction Pathway antibodies	Cardiac Muscle Contraction Pathway Diagram

Diseases associated with anti-ATP1A3 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>92 publications with ATP1A3 and Nervous System Diseases
Dystonia Antibodies	>73 publications with ATP1A3 and Dystonia
Alternating hemiplegia of childhood Antibodies	>59 publications with ATP1A3 and Alternating hemiplegia of childhood
Brain Diseases Antibodies	>52 publications with ATP1A3 and Brain Diseases
Parkinsonian Disorders Antibodies	>21 publications with ATP1A3 and Parkinsonian Disorders
Ataxia Antibodies	>17 publications with ATP1A3 and Ataxia
Seizures Antibodies	>15 publications with ATP1A3 and Seizures
Dystonia 12 Antibodies	>14 publications with ATP1A3 and Dystonia 12
Atrophy Antibodies	>14 publications with ATP1A3 and Atrophy
Disease Models, Animal Antibodies	>13 publications with ATP1A3 and Disease Models, Animal

Organs/Tissues associated with anti-ATP1A3 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>57 publications with ATP1A3 and Brain
Muscle Antibodies	>23 publications with ATP1A3 and Muscle
Heart Antibodies	>13 publications with ATP1A3 and Heart
Nerve Antibodies	>9 publications with ATP1A3 and Nerve
Blood Antibodies	>9 publications with ATP1A3 and Blood
Eye Antibodies	>6 publications with ATP1A3 and Eye
Kidney Antibodies	>3 publications with ATP1A3 and Kidney
Embryonic Tissue Antibodies	>2 publications with ATP1A3 and Embryonic Tissue
Thyroid Antibodies	>2 publications with ATP1A3 and Thyroid