Rabbit Anti-ATP6V1C2 Polyclonal Antibody – Cat# MBS6276694

ATP6V1C2 Antibody – Rabbit Polyclonal

Name: ATP6V1C2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6276694
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6276694

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting,… More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ATP6V1C2, Polyclonal Antibody

Full Product Name

ATP6V1C2, ID (ATP6V1C2, V-type proton ATPase subunit C 2, Vacuolar proton pump subunit C 2) (MaxLight 405)

Product Gene Name

anti-ATP6V1C2 antibody

Product Synonym Names

ATP6V1C2; V-type proton ATPase subunit C 2; Vacuolar proton pump subunit C 2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

3D Structure

ModBase 3D Structure for Q8NEY4

Immunogen

ATP6V1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-304 amino acids from the Central region of human ATP6V1C2.

Conjugate

MaxLight405

Note

Preservative Free

Product Categories/Family for anti-ATP6V1C2 antibody

Antibodies; Enzymes; ATPase

Applications Tested/Suitable for anti-ATP6V1C2 antibody

Western Blot (WB), FLISA

Application Notes for anti-ATP6V1C2 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-ATP6V1C2 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Gruber, G. Biochem. Soc. Trans. 33 (PT 4), 883-885 (2005): Morel, N. Biol. Cell 95(7):453-457(2003). Smith, A.N., et al. Mol. Cell 12(4):801-803(2003). Kawasaki-Nishi, S., et al. FEBS Lett. 545(1):76-85(2003).

Other Notes

Small volumes of anti-ATP6V1C2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATP6V1C2 purchase

MBS6276694 is an antibody targeting ATP6V1C2. Also known as ATP6V1C2, ID (ATP6V1C2, V-type proton ATPase subunit C 2, Vacuolar proton pump subunit C 2) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP6V1C2. It may not necessarily be applicable to this product.

NCBI GI #

47717098

NCBI GeneID

245973

NCBI Accession #

NP_653184.2

UniProt Primary Accession #

Q8NEY4

UniProt Related Accession #

Q8NEY4

GenBank Nucleotide #

NP_653184.2

NCBI Official Full Name

V-type proton ATPase subunit C 2 isoform b

NCBI Official Synonym Full Names

ATPase H+ transporting V1 subunit C2

NCBI Official Symbol

ATP6V1C2

NCBI Official Synonym Symbols

VMA5; ATP6C2

UniProt Protein Name

V-type proton ATPase subunit C 2

UniProt Synonym Protein Names

Vacuolar proton pump subunit C 2

Protein Family

V-type proton ATPase

UniProt Gene Name

ATP6V1C2

UniProt Synonym Gene Names

V-ATPase subunit C 2

UniProt Entry Name

VATC2_HUMAN

NCBI Protein Information

V-type proton ATPase subunit C 2

UniProt Comments for ATP6V1C2

ATP6V1C2: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase C subunit family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.3.14; Energy Metabolism - oxidative phosphorylation; Hydrolase

Chromosomal Location of Human Ortholog: -

Cellular Component: lysosomal membrane; cytosol

Molecular Function: hydrogen-exporting ATPase activity, phosphorylative mechanism; protein dimerization activity

Biological Process: interaction with host; cellular iron ion homeostasis; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; transferrin transport; transmembrane transport; positive regulation of Wnt receptor signaling pathway

Research Articles on ATP6V1C2

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ATP6V1C2 antibody

Reference Product	PubMed Publications
ATP6V0D2 antibody	>2 publications with ATP6V1C2 and ATP6V0D2
ATP6V1B1 antibody	>2 publications with ATP6V1C2 and ATP6V1B1
ATP6V0D1 antibody	>1 publications with ATP6V1C2 and ATP6V0D1
ATP6V1B2 antibody	>1 publications with ATP6V1C2 and ATP6V1B2
ATP6V1E2 antibody	>1 publications with ATP6V1C2 and ATP6V1E2
ATP6V1A antibody	>1 publications with ATP6V1C2 and ATP6V1A

Pathways associated with anti-ATP6V1C2 antibody

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Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Infectious Disease Pathway antibodies	Infectious Disease Pathway Diagram
Insulin Receptor Recycling Pathway antibodies	Insulin Receptor Recycling Pathway Diagram
Ion Channel Transport Pathway antibodies	Ion Channel Transport Pathway Diagram
Iron Uptake And Transport Pathway antibodies	Iron Uptake And Transport Pathway Diagram
Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway antibodies	Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway Diagram

Diseases associated with anti-ATP6V1C2 antibody

Disease Name	Pubmed Publications
Hearing Loss Antibodies	>1 publications with ATP6V1C2 and Hearing Loss
Nervous System Diseases Antibodies	>1 publications with ATP6V1C2 and Nervous System Diseases
Kidney Diseases Antibodies	>1 publications with ATP6V1C2 and Kidney Diseases

Organs/Tissues associated with anti-ATP6V1C2 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>3 publications with ATP6V1C2 and Kidney
Lung Antibodies	>2 publications with ATP6V1C2 and Lung
Embryonic Tissue Antibodies	>1 publications with ATP6V1C2 and Embryonic Tissue
Uncharacterized Tissue Antibodies	>1 publications with ATP6V1C2 and Uncharacterized Tissue
Testis Antibodies	>1 publications with ATP6V1C2 and Testis
Brain Antibodies	>1 publications with ATP6V1C2 and Brain