Rabbit Anti-ATRN Polyclonal Antibody – Cat# MBS2151225

Attractin (ATRN) Antibody – Rabbit Polyclonal

Name: ATRN Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2151225
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2151225

MBS2151225 is an antibody targeting ATRN. Also known as APC_Cy7-Linked Polyclonal Antibody to Attractin (ATRN). Reactive in Human. Host: Rabbit. More details

$445 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Attractin (ATRN), Polyclonal Antibody

Full Product Name

APC_Cy7-Linked Polyclonal Antibody to Attractin (ATRN)

Product Gene Name

anti-ATRN antibody

Product Synonym Names

Attractin; DPPT-L; MGCA; Mahogany homolog

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Purity/Purification

Affinity Chromatography

Concentration

>=0.1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)

Preparation and Storage

Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.

Matching Pairs

Antibody: ATRN (MBS2151225)
Immunogen: ATRN (MBS2097574)

Matching Pairs

Unconjugated Antibody: ATRN (MBS2152800)
APC-CY7 Conjugated Antibody: ATRN (MBS2151225)

Molecular Weight

158,537 Da

Immunogen Sequence Positions

Ala84~Tyr245

Chromosome Location

Chromosome: 20; NC_000020.10 (3451665..3631769). Location: 20p13

OMIM

603130

3D Structure

ModBase 3D Structure for O75882

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Conjugation

APC Cy7

Product Categories/Family for anti-ATRN antibody

Polyclonal Antibodies (Primary Abs); Primary, APC_Cy7-conjugated; Infection immunity

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-ATRN antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Application Notes for anti-ATRN antibody

WB: 0.2-2ug/mL, 1:250-2500
IHC: 5-20ug/mL, 1:25-100
ICC: 5-20ug/mL, 1:25-100

Other Notes

Small volumes of anti-ATRN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ATRN. It may not necessarily be applicable to this product.

NCBI GI #

21450863

NCBI GeneID

8455

NCBI Accession #

NP_647538.1

UniProt Primary Accession #

O75882

UniProt Secondary Accession #

O60295; O95414; Q3MIT3; Q5TDA2; Q5TDA4; Q5VYW3; Q9NTQ3; Q9NTQ4; Q9NU01; Q9NZ57; A8KAE5

UniProt Related Accession #

O75882

GenBank Nucleotide #

NM_139322.2

NCBI Official Full Name

attractin isoform 2 preproprotein

NCBI Official Synonym Full Names

attractin

NCBI Official Symbol

ATRN

NCBI Official Synonym Symbols

MGCA; DPPT-L

UniProt Protein Name

Attractin

UniProt Synonym Protein Names

DPPT-L; Mahogany homolog

UniProt Gene Name

ATRN

UniProt Synonym Gene Names

KIAA0548; MGCA

UniProt Entry Name

ATRN_HUMAN

NCBI Protein Information

attractin; attractin-2; mahogany homolog; mahogany protein

NCBI Summary for ATRN

Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, May 2011]

UniProt Comments for ATRN

ATRN: Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: extracellular space; integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: receptor activity; carbohydrate binding

Biological Process: myelination; pigmentation; regulation of multicellular organism growth; cerebellum development; response to oxidative stress; inflammatory response

Research Articles on ATRN

1. The levels of both dipeptidyl-peptidase 4 and attractin in circulating monocytes were significantly higher in obese subjects as compared with levels in lean controls or in subjects with type 2 diabetes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ATRN antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>10 publications with ATRN and Brain Diseases
Neurodegenerative Diseases Antibodies	>6 publications with ATRN and Neurodegenerative Diseases
Disease Models, Animal Antibodies	>4 publications with ATRN and Disease Models, Animal
Seizures Antibodies	>3 publications with ATRN and Seizures
Weight Loss Antibodies	>3 publications with ATRN and Weight Loss
Growth Disorders Antibodies	>1 publications with ATRN and Growth Disorders
Abnormalities, Multiple Antibodies	>1 publications with ATRN and Abnormalities, Multiple
Drug Toxicity Antibodies	>1 publications with ATRN and Drug Toxicity
Neoplasms, Experimental Antibodies	>1 publications with ATRN and Neoplasms, Experimental
Inflammation Antibodies	>1 publications with ATRN and Inflammation

Organs/Tissues associated with anti-ATRN antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>24 publications with ATRN and Brain
Blood Antibodies	>12 publications with ATRN and Blood
Nerve Antibodies	>12 publications with ATRN and Nerve
Skin Antibodies	>9 publications with ATRN and Skin
Spinal Cord Antibodies	>7 publications with ATRN and Spinal Cord
Testis Antibodies	>5 publications with ATRN and Testis
Epididymis Antibodies	>4 publications with ATRN and Epididymis
Adipose Tissue Antibodies	>1 publications with ATRN and Adipose Tissue
Connective Tissue Antibodies	>1 publications with ATRN and Connective Tissue
Muscle Antibodies	>1 publications with ATRN and Muscle