Rabbit Anti-BCCIP Polyclonal Antibody – Cat# MBS8107354

BCCIP Antibody – Rabbit Polyclonal

Name: BCCIP Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS8107354
Price: 175 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8107354

BCCIP was originally identified as a BRCA2 and CDKN1A interacting protein that has been implicated in maintenance of genomic stability, cell cycle regulation, and microtubule dynamics. The secondary genetic alternations may overcome the progression… More details

$175 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BCCIP, Polyclonal Antibody

Full Product Name

Anti-BCCIP Antibody, Rabbit Polyclonal

Product Gene Name

anti-BCCIP antibody

Product Synonym Names

BRCA2/BCCIP Antibody, Rabbit PAb, Antigen Affinity Purified; BRCA2 and CDKN1A interacting protein; Anti-TOK-1 Antibody; Anti-TOK1 Antibody

Clonality

Polyclonal

Isotype

Rabbit IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid; 0.2um filtered solution in PBS

Purity/Purification

Protein A & Antigen Affinity

Specificity

Human BRCA2/BCCIP

Preparation and Storage

This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Molecular Weight

33,242 Da

Immunogen

Recombinant Human BRCA2/BCCIP protein

Conjugation

Unconjugated

Preparation

Produced in rabbits immunized with purified, recombinant Human BRCA2/BCCIP (rh BRCA2/BCCIP). BRCA2/BCCIP specific IgG was purified by Human BRCA2/BCCIP affinity chromatography.

Applications Tested/Suitable for anti-BCCIP antibody

ELISA (EIA)

Application Notes for anti-BCCIP antibody

ELISA: 1:5000-1:10,000

Other Notes

Small volumes of anti-BCCIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCCIP purchase

MBS8107354 is an antibody targeting BCCIP. Also known as Anti-BCCIP Antibody, Rabbit Polyclonal. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BCCIP. It may not necessarily be applicable to this product.

NCBI GI #

14602523

NCBI GeneID

56647

NCBI Accession #

AAH09771.1

UniProt Secondary Accession #

Q8ND15; Q96GC4; Q9P288; B3KP45

UniProt Related Accession #

Q9P287

NCBI Official Full Name

BRCA2 and CDKN1A interacting protein

NCBI Official Synonym Full Names

BRCA2 and CDKN1A interacting protein

NCBI Official Symbol

BCCIP

NCBI Official Synonym Symbols

TOK1; TOK-1

Protein Family

BRCA2 and CDKN1A-interacting protein

NCBI Protein Information

BRCA2 and CDKN1A-interacting protein; BCCIPalpha; BCCIPbeta; BRCA2 and Cip1/p21 interacting protein; TOK-1alpha; TOK-1beta; cdk inhibitor p21 binding protein; p21- and CDK-associated protein 1; protein TOK-1

NCBI Summary for BCCIP

This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Research Articles on BCCIP

1. Results indicate that BCCIP germ line mutations are unlikely to be a major contributor to familial breast/ovarian cancer risk in our population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BCCIP antibody

Reference Product	PubMed Publications
BRCA2 antibody	>25 publications with BCCIP and BRCA2
CDKN1A antibody	>18 publications with BCCIP and CDKN1A
RAD51 antibody	>6 publications with BCCIP and RAD51
CDK2 antibody	>3 publications with BCCIP and CDK2
UROS antibody	>1 publications with BCCIP and UROS
CDK4 antibody	>1 publications with BCCIP and CDK4

Diseases associated with anti-BCCIP antibody

Disease Name	Pubmed Publications
Death Antibodies	>2 publications with BCCIP and Death
Central Nervous System Diseases Antibodies	>2 publications with BCCIP and Central Nervous System Diseases
Ataxia Antibodies	>1 publications with BCCIP and Ataxia
Skin Neoplasms Antibodies	>1 publications with BCCIP and Skin Neoplasms
Uterine Cervical Neoplasms Antibodies	>1 publications with BCCIP and Uterine Cervical Neoplasms
Kidney Diseases Antibodies	>1 publications with BCCIP and Kidney Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with BCCIP and Carcinoma, Hepatocellular
Intestinal Neoplasms Antibodies	>1 publications with BCCIP and Intestinal Neoplasms

Organs/Tissues associated with anti-BCCIP antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>2 publications with BCCIP and Prostate
Kidney Antibodies	>2 publications with BCCIP and Kidney
Ovary Antibodies	>1 publications with BCCIP and Ovary
Liver Antibodies	>1 publications with BCCIP and Liver
Embryonic Tissue Antibodies	>1 publications with BCCIP and Embryonic Tissue
Uterus Antibodies	>1 publications with BCCIP and Uterus
Testis Antibodies	>1 publications with BCCIP and Testis
Skin Antibodies	>1 publications with BCCIP and Skin
Brain Antibodies	>1 publications with BCCIP and Brain