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BCL7A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9413399

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the… More details

$260 / 0.05 mL +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
BCL7A, Polyclonal Antibody
Full Product Name
BCL7A Antibody
Product Gene Name
Product Synonym Names
B-cell CLL/lymphoma 7 family member A; B-cell CLL/lymphoma 7A; B-cell CLL/lymphoma-7; BCL7; BCL7A
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1.0 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total BCL7A protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
25,029 Da
OMIM
601406
3D Structure
ModBase 3D Structure for Q4VC05
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human BCL7A.
Target Name
BCL7A

Product Categories/Family for anti-BCL7A antibody

Applications Tested/Suitable for anti-BCL7A antibody
Western Blot (WB)
Application Notes for anti-BCL7A antibody
Western blotting: 1:500~1:3000

Western Blot (WB) of anti-BCL7A antibody

Western blot analysis of extracts from HuvEc cells, using BCL7A antibody.
Rabbit Anti-BCL7A Polyclonal Antibody – Cat# MBS9413399

Other Notes

Small volumes of anti-BCL7A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCL7A purchase

MBS9413399 is an antibody targeting BCL7A. Also known as BCL7A Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BCL7A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
B-cell CLL/lymphoma 7 protein family member A isoform b
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 7A
NCBI Official Symbol
BCL7A
NCBI Official Synonym Symbols
BCL7
UniProt Protein Name
B-cell CLL/lymphoma 7 protein family member A
UniProt Gene Name
BCL7A
UniProt Entry Name
BCL7A_HUMAN
NCBI Protein Information
B-cell CLL/lymphoma 7 protein family member A

NCBI Summary for BCL7A

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for BCL7A

Bcl-7A: Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions. Belongs to the BCL7 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding

Chromosomal Location of Human Ortholog: 12q24.13

Biological Process: negative regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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