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BLR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9450431

MBS9450431 is an antibody targeting Blr1. Also known as Blr1 Polyclonal Conjugated Antibody. Reactive in Human. Host: Rabbit. More details

$435 / 0.1 mL (Biotin) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Blr1, Polyclonal Antibody
Full Product Name
Blr1 Polyclonal Conjugated Antibody
Product Gene Name
anti-Blr1 antibody
Product Synonym Names
CXCR5; BLR1; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15; CD185
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Specificity
Blr1 polyclonal antibody detects endogenous levels of Blr1 protein.
Preparation and Storage
Store at 4 degree C for 6 months.
Molecular Weight
36,676 Da
OMIM
601613
3D Structure
ModBase 3D Structure for P32302
Immunogen
Synthesized peptide derived from the N-terminal region of human Blr1.
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Applications Tested/Suitable for anti-Blr1 antibody
Most Applications
Application Notes for anti-Blr1 antibody
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000

Other Notes

Small volumes of anti-Blr1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Blr1. It may not necessarily be applicable to this product.

NCBI GI #
416718
NCBI GeneID
643
NCBI Accession #
P32302.1
UniProt Primary Accession #
P32302
UniProt Secondary Accession #
Q14811
UniProt Related Accession #
P32302
NCBI Official Full Name
C-X-C chemokine receptor type 5
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 5
NCBI Official Symbol
CXCR5
NCBI Official Synonym Symbols
BLR1; CD185; MDR15
UniProt Protein Name
C-X-C chemokine receptor type 5
UniProt Synonym Protein Names
Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15; CD_antigen: CD185
UniProt Gene Name
CXCR5
UniProt Synonym Gene Names
BLR1; MDR15; CXC-R5; CXCR-5; MDR-15
UniProt Entry Name
CXCR5_HUMAN
NCBI Protein Information
C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)

NCBI Summary for Blr1

This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
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UniProt Comments for Blr1

CXCR5: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; C-X-C chemokine receptor activity

Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; B cell activation; immune response; cell motility; chemotaxis; lymph node development
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Research Articles on Blr1

1. expression of CXCR5 was significantly associated with both stage and lymph node metastasis, but not with tumor size, tumor differentiation grade, or menopausal status of the patient.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Blr1 antibody

 Reference Product  PubMed Publications
 CXCL13 antibody  >184 publications with Blr1 and CXCL13
 CCL19 antibody  >31 publications with Blr1 and CCL19
 CCL21 antibody  >28 publications with Blr1 and CCL21
 CCL5 antibody  >13 publications with Blr1 and CCL5
 CCL20 antibody  >12 publications with Blr1 and CCL20
 CCL25 antibody  >4 publications with Blr1 and CCL25
 CCL28 antibody  >2 publications with Blr1 and CCL28
 CCL27 antibody  >1 publications with Blr1 and CCL27

Pathways associated with anti-Blr1 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with anti-Blr1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >79 publications with Blr1 and Inflammation
 Necrosis Antibodies  >41 publications with Blr1 and Necrosis
 Nervous System Diseases Antibodies  >37 publications with Blr1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >30 publications with Blr1 and Disease Models, Animal
 Carcinoma Antibodies  >19 publications with Blr1 and Carcinoma
 Lung Diseases Antibodies  >17 publications with Blr1 and Lung Diseases
 Kidney Diseases Antibodies  >16 publications with Blr1 and Kidney Diseases
 Neoplasms, Experimental Antibodies  >15 publications with Blr1 and Neoplasms, Experimental
 Skin Diseases Antibodies  >14 publications with Blr1 and Skin Diseases
 Liver Diseases Antibodies  >11 publications with Blr1 and Liver Diseases

Organs/Tissues associated with anti-Blr1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >479 publications with Blr1 and Blood
 Lymph Node Antibodies  >194 publications with Blr1 and Lymph Node
 Lymph Antibodies  >109 publications with Blr1 and Lymph
 Spleen Antibodies  >72 publications with Blr1 and Spleen
 Pharynx Antibodies  >29 publications with Blr1 and Pharynx
 Thymus Antibodies  >25 publications with Blr1 and Thymus
 Lung Antibodies  >22 publications with Blr1 and Lung
 Skin Antibodies  >16 publications with Blr1 and Skin
 Intestine Antibodies  >14 publications with Blr1 and Intestine
 Prostate Antibodies  >10 publications with Blr1 and Prostate
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