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BMP8B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9408481

Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis By similarity.Oezkaynak E., J. Biol. Chem. 267:25220-25227(1992).Onishi… More details

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Product Overview

Online Datasheet in PDF
Product Name
BMP8B, Polyclonal Antibody
Full Product Name
BMP8B Antibody
Product Gene Name
Product Synonym Names
Bone morphogenetic protein 8B; BMP-8B; BMP-8; BMP8; Osteogenic protein 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1.0 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total BMP8B protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
39,151 Da
OMIM
602284
3D Structure
ModBase 3D Structure for P34820
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human BMP8B.
Target Name
BMP8B

Product Categories/Family for anti-BMP8B antibody

Applications Tested/Suitable for anti-BMP8B antibody
Western Blot (WB)
Application Notes for anti-BMP8B antibody
Western blotting: 1:500~1:3000

Western Blot (WB) of anti-BMP8B antibody

Western blot analysis of extracts from 293 cells and A549 cells, using BMP8B antibody.
Rabbit Anti-BMP8B Polyclonal Antibody – Cat# MBS9408481

Other Notes

Small volumes of anti-BMP8B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMP8B purchase

MBS9408481 is an antibody targeting BMP8B. Also known as BMP8B Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BMP8B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bone morphogenetic protein 8B preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 8b
NCBI Official Symbol
BMP8B
NCBI Official Synonym Symbols
OP2; BMP8
UniProt Protein Name
Bone morphogenetic protein 8B
UniProt Synonym Protein Names
Osteogenic protein 2; OP-2
UniProt Gene Name
BMP8B
UniProt Synonym Gene Names
BMP8; BMP-8; BMP-8B; OP-2
UniProt Entry Name
BMP8B_HUMAN
NCBI Protein Information
bone morphogenetic protein 8B

NCBI Summary for BMP8B

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]
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UniProt Comments for BMP8B

BMP8B: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: 1p35-p32

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: regulation of apoptosis; BMP signaling pathway; ossification; regulation of MAPKKK cascade; cartilage development; skeletal development; cell development; growth
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BMP8B antibody

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