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BOK Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150551

BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BOK, Polyclonal Antibody
Full Product Name
BOK Antibody
Product Gene Name
Product Synonym Names
BOK; BOKL; BCL2L9; Bcl-2-related ovarian killer protein; Bcl-2-like protein 9; hBOK; BCL2-related ovarian killer
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
BOK Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least three isoforms of BOK are known to exist; this antibody will not detect the smallest isoform. BOK antibody is predicted to not cross-react with other Bcl-2 protein family members
Preparation and Storage
BOK antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
BOK peptide (MBS152676) is used for blocking the activity of BOK antibody (MBS150551)
Molecular Weight
23,280 Da
OMIM
605404
3D Structure
ModBase 3D Structure for Q9UMX3
Conjugate
Unconjugated
Immunogen
BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK.
Buffer
BOK Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-BOK antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-BOK antibody
BOK antibody can be used for detection of BOK by immunohistochemistry at 5 mug/mL.

Immunohistochemistry (IHC) of anti-BOK antibody

Immunohistochemistry of BOK in human brain tissue with BOK antibody at 5 μg/mL.
Rabbit Anti-BOK Polyclonal Antibody – Cat# MBS150551

Other Notes

Small volumes of anti-BOK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BOK purchase

MBS150551 is an antibody targeting BOK. Also known as BOK Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BOK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bcl-2-related ovarian killer protein
NCBI Official Synonym Full Names
BCL2-related ovarian killer
NCBI Official Symbol
BOK
NCBI Official Synonym Symbols
BOKL; BCL2L9
UniProt Protein Name
Bcl-2-related ovarian killer protein
UniProt Synonym Protein Names
Bcl-2-like protein 9; Bcl2-L-9
UniProt Gene Name
BOK
UniProt Synonym Gene Names
BCL2L9; hBOK; Bcl2-L-9
UniProt Entry Name
BOK_HUMAN
NCBI Protein Information
bcl-2-related ovarian killer protein; hBOK; bcl2-L-9; bcl-2-like protein 9

NCBI Summary for BOK

The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011]
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UniProt Comments for BOK

BOK: May play a role in apoptosis. Belongs to the Bcl-2 family.

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; mitochondrial outer membrane; mitochondrion; mitochondrial membrane; cytoplasm; integral to membrane; nucleus

Molecular Function: BH domain binding; protein binding; protein homodimerization activity; protein heterodimerization activity

Biological Process: caspase activation; cell proliferation; neuron apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis; apoptosis; male gonad development; oligodendrocyte differentiation; brain development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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