Rabbit Anti-BTN3A3 Polyclonal Antibody – Cat# MBS6279282

BTN3A3 Antibody – Rabbit Polyclonal

Name: BTN3A3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6279282
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6279282

MaxLight550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor546, 555, DyLight549, Cy3, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BTN3A3, Polyclonal Antibody

Full Product Name

BTN3A3, NT (BTN3A3, BTF3, Butyrophilin subfamily 3 member A3) (MaxLight 550)

Product Gene Name

anti-BTN3A3 antibody

Product Synonym Names

BTN3A3; BTF3; Butyrophilin subfamily 3 member A3

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

613595

3D Structure

ModBase 3D Structure for O00478

Immunogen

BTN3A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human BTN3A3.

Conjugate

MaxLight550

Note

Preservative Free

Product Categories/Family for anti-BTN3A3 antibody

Antibodies; Proteins

Applications Tested/Suitable for anti-BTN3A3 antibody

Western Blot (WB), FLISA

Application Notes for anti-BTN3A3 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-BTN3A3 antibody

Smith, I.A., et al. J. Immunol. 184(7):3514-3525(2010). Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004). Rhodes, D.A., et al. Genomics 71(3):351-362(2001). Henry, J., et al. Immunol. Today 20(6):285-288(1999). Ruddy, D.A., et al. Genome Res. 7(5):441-456(1997).

Other Notes

Small volumes of anti-BTN3A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BTN3A3 purchase

MBS6279282 is an antibody targeting BTN3A3. Also known as BTN3A3, NT (BTN3A3, BTF3, Butyrophilin subfamily 3 member A3) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BTN3A3. It may not necessarily be applicable to this product.

NCBI GI #

261490684

NCBI GeneID

10384

NCBI Accession #

NP_932078.2

UniProt Primary Accession #

O00478

UniProt Related Accession #

O00478

GenBank Nucleotide #

NP_932078.2

NCBI Official Full Name

butyrophilin subfamily 3 member A3 isoform b

NCBI Official Synonym Full Names

butyrophilin subfamily 3 member A3

NCBI Official Symbol

BTN3A3

NCBI Official Synonym Symbols

BTF3; BTN3.3

UniProt Protein Name

Butyrophilin subfamily 3 member A3

Protein Family

Butyrophilin subfamily

UniProt Gene Name

BTN3A3

UniProt Synonym Gene Names

BTF3

UniProt Entry Name

BT3A3_HUMAN

NCBI Protein Information

butyrophilin subfamily 3 member A3

NCBI Summary for BTN3A3

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

UniProt Comments for BTN3A3

Function: Plays a role in T-cell responses in the adaptive immune response. Ref.10

Subunit structure: Homodimer. Ref.11

Subcellular location: Cell membrane; Single-pass type I membrane protein Ref.9 Ref.10.

Tissue specificity: Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes. Ref.8

Post-translational modification: N-glycosylated. Ref.8

Sequence similarities: Belongs to the immunoglobulin superfamily. BTN/MOG family.Contains 1 B30.2/SPRY domain.Contains 2 Ig-like V-type (immunoglobulin-like) domains.

Research Articles on BTN3A3

1. This study identified that CGPs was found to significantly correlate with the differential expression and methylation of genes encoding butyrophilin, subfamily 3, member A3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.