Rabbit Anti-BubR1 Polyclonal Antibody – Cat# MBS6004238

Human Small Intestine (formalin-fixed, paraffin-embedded) stained with BUB1 antibody at 5ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.

BubR1 Antibody – Rabbit Polyclonal

Name: BubR1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6004238
Price: 785 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6004238

This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy… More details

$785 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BUB1 (BubR1), Polyclonal Antibody

Full Product Name

BUB1, NT (Mitotic Checkpoint Serine/Threonine-protein Kinase BUB1, hBub1, BUB1A, BUB1L)

Product Gene Name

anti-BubR1 antibody

Product Synonym Names

Anti -BUB1, NT (Mitotic Checkpoint Serine/Threonine-protein Kinase BUB1, hBub1, BUB1A, BUB1L)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human BUB1. Species sequence homology: Mouse.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Chromosome Location

Chromosome: 2R; NT_033778.3 (1856604..1861890, complement). Location: 42A5-42A6

Immunogen

Synthetic peptide corresponding to 19aa from near the N-terminal of human Bub1 (KLH).

Product Categories/Family for anti-BubR1 antibody

Antibodies; Abs to DNA Replication; Repair

Applications Tested/Suitable for anti-BubR1 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-BubR1 antibody

Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 4ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Other Notes

Small volumes of anti-BubR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BubR1 purchase

MBS6004238 is an antibody targeting BubR1. Also known as BUB1, NT (Mitotic Checkpoint Serine/Threonine-protein Kinase BUB1, hBub1, BUB1A, BUB1L). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BubR1. It may not necessarily be applicable to this product.

NCBI GI #

17137586

NCBI GeneID

35522

NCBI Accession #

NP_477382.1

UniProt Related Accession #

Q9XZ59

GenBank Nucleotide #

NM_058034.4

NCBI Official Full Name

Bub1-related kinase

NCBI Official Synonym Full Names

Bub1-related kinase

NCBI Official Symbol

BubR1

NCBI Official Synonym Symbols

31/13; BcDNA:LD23835; bub1; Bub1; BUB1; bubr1; bubR1; BUBR1; CG 7838; CG7838; dBUB1; Dmbub1; DmBUB1; DmelCG7838; l(2)k03113; l(2)k06109; mcl(2)Z1525

Protein Family

Mitotic spindle checkpoint protein

NCBI Protein Information

CG7838 gene product from transcript CG7838-RA; Bub1; Bub1-related kinase; BubR1-PA; CG7838-PA; bub related one; mcl(2)Z1525

Research Articles on BubR1

1. a model in which Polo controls Mps1-dependent BubR1 phosphorylation to promote Cdc20 kinetochore recruitment and sustained SAC function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.