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CA5B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2559645

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CA5B, Polyclonal Antibody
Full Product Name
CA5B Polyclonal Antibody
Product Gene Name
anti-CA5B antibody
Product Synonym Names
CA VB; Carbonate dehydratase VB; Carbonic anhydrase 5B; Mitochondrial; Carbonic anhydrase VB; Carbonic anhydrase VB; Mitochondrial
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.9mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
OMIM
300230
3D Structure
ModBase 3D Structure for Q9Y2D0
Immunogen
Synthetic peptide of human CA5B
Conjugation
Unconjugated

Product Categories/Family for anti-CA5B antibody

Metabolism; Signal Transduction
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CA5B antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CA5B antibody
IHC: 1:40-1:200
ELISA: 1:5000-1:10000

Immunohistochemistry (IHC) of anti-CA5B antibody

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CA5B Polyclonal Antibody at dilution of 1:65(×200)
Rabbit Anti-CA5B Polyclonal Antibody – Cat# MBS2559645

Other Notes

Small volumes of anti-CA5B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CA5B purchase

MBS2559645 is an antibody targeting CA5B. Also known as CA5B Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CA5B. It may not necessarily be applicable to this product.

NCBI GI #
6005723
NCBI GeneID
11238
NCBI Accession #
NP_009151.1
UniProt Primary Accession #
Q9Y2D0
UniProt Related Accession #
Q9Y2D0
GenBank Nucleotide #
NP_009151.1
NCBI Official Full Name
carbonic anhydrase 5B, mitochondrial
NCBI Official Synonym Full Names
carbonic anhydrase 5B
NCBI Official Symbol
CA5B
NCBI Official Synonym Symbols
CAVB; CA-VB
UniProt Protein Name
Carbonic anhydrase 5B, mitochondrial
UniProt Synonym Protein Names
Carbonate dehydratase VB; Carbonic anhydrase VB
Protein Family
Carbonic anhydrase
UniProt Gene Name
CA5B
UniProt Synonym Gene Names
CA-VB
UniProt Entry Name
CAH5B_HUMAN
NCBI Protein Information
carbonic anhydrase 5B, mitochondrial

NCBI Summary for CA5B

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes carbonic anhydrase 5B. CA5B, and the related CA5A gene, has its expression localized in the mitochondria though CA5B has a wider tissue distribution than CA5A, which is restricted to the liver, kidneys, and skeletal muscle. A carbonic anhydrase pseudogene (CA5BP1) is adjacent to the CA5B gene and these two loci produce CA5BP1-CA5B readthrough transcripts. [provided by RefSeq, Jan 2019]
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UniProt Comments for CA5B

CA5B: Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family.

Protein type: Lyase; Energy Metabolism - nitrogen; EC 4.2.1.1; Mitochondrial

Chromosomal Location of Human Ortholog: Xp21.1

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: carbonate dehydratase activity; zinc ion binding

Biological Process: bicarbonate transport; one-carbon compound metabolic process
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Research Articles on CA5B

1. In 10 of 96 patients, mutations in CA5A were identified on both alleles but none in CA5B. Exhibiting decreased enzyme activity or thermal stability, all CAVA mutations were proven to cause disease, whereas the three variants showed no relevant effect

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CA5B antibody

 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Reversible Hydration Of Carbon Dioxide Pathway antibodies  Reversible Hydration Of Carbon Dioxide Pathway Diagram
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