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CA6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9209555

The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CA6, Polyclonal Antibody
Full Product Name
CA6 Antibody (C-term)
Product Gene Name
Product Synonym Names
Carbonic anhydrase 6; Carbonate dehydratase VI; Carbonic anhydrase VI; CA-VI; Salivary carbonic anhydrase; Secreted carbonic anhydrase; CA6
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.5 (lot specific)
Specificity
This CA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-308 amino acids from the C-terminal region of human CA6.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CA6 peptide (MBS9228398) is used for blocking the activity of CA6 antibody (MBS9209555)
Molecular Weight
35367
Immunogen Sequence Positions
279-308
OMIM
114780
3D Structure
ModBase 3D Structure for P23280
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN

Product Categories/Family for anti-CA6 antibody

Applications Tested/Suitable for anti-CA6 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-CA6 antibody
WB~~1:1000

Western Blot (WB) of anti-CA6 antibody

Western blot analysis of CA6 Antibody (C-term) in CEM cell line lysates (35ug/lane). CA6 (arrow) was detected using the purified Pab.
Rabbit Anti-CA6 Polyclonal Antibody – Cat# MBS9209555

Immunohistochemistry (IHC) of anti-CA6 antibody

CA6 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CA6 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-CA6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9209555

Flow Cytometry (FC/FACS) of anti-CA6 antibody

CA6 Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-CA6 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS9209555

Product References and Citations for anti-CA6 antibody

Nishimori, I., et al. Bioorg. Med. Chem. 15(15):5351-5357(2007)
Karhumaa, P., et al. Proc. Natl. Acad. Sci. U.S.A. 98(20):11604-11608(2001)
Breton, S. JOP 2 (4 SUPPL), 159-164 (2001) :
Leinonen, J., et al. J. Histochem. Cytochem. 49(5):657-662(2001)

Other Notes

Small volumes of anti-CA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CA6 purchase

MBS9209555 is an antibody targeting CA6. Also known as CA6 Antibody (C-term). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CA6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
carbonic anhydrase 6 isoform 1
NCBI Official Synonym Full Names
carbonic anhydrase VI
NCBI Official Symbol
CA6
NCBI Official Synonym Symbols
CA-VI; GUSTIN
UniProt Protein Name
Carbonic anhydrase 6
UniProt Synonym Protein Names
Carbonate dehydratase VI; Carbonic anhydrase VI; CA-VI; Salivary carbonic anhydrase; Secreted carbonic anhydrase
Protein Family
UniProt Gene Name
CA6
UniProt Synonym Gene Names
CA-VI
UniProt Entry Name
CAH6_HUMAN
NCBI Protein Information
carbonic anhydrase 6

UniProt Comments for CA6

CA6: Reversible hydration of carbon dioxide. Its role in saliva is unknown. Belongs to the alpha-carbonic anhydrase family.

Protein type: Secreted; Energy Metabolism - nitrogen; EC 4.2.1.1; Lyase; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36.2

Cellular Component: extracellular space; cytoplasm; extracellular region

Molecular Function: carbonate dehydratase activity; zinc ion binding

Biological Process: bicarbonate transport; one-carbon compound metabolic process; detection of chemical stimulus involved in sensory perception of bitter taste
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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