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CARD17 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS627465

MBS627465 is an antibody targeting CARD17. Also known as CARD17 (Caspase Recruitment Domain Family, Member 17, INCA, Inhibitory Caspase Recruitment Domain Protein). Reactive in Human. Host: Goat. More details

$835 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CARD17, Polyclonal Antibody
Full Product Name
CARD17 (Caspase Recruitment Domain Family, Member 17, INCA, Inhibitory Caspase Recruitment Domain Protein)
Product Gene Name
Product Synonym Names
Anti -CARD17 (Caspase Recruitment Domain Family, Member 17, INCA, Inhibitory Caspase Recruitment Domain Protein)
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by peptide affinity chromatography.
Specificity
Recognizes human CARD17.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
11,868 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (104963196..104972158, complement). Location: 11q22.3
OMIM
609490
3D Structure
ModBase 3D Structure for Q5XLA6
Immunogen
Synthetic peptide corresponding to C-NHLTTQDSQIVLPS, from the C-Terminus of human CARD17 (NP_001007233.1).
Applications Tested/Suitable for anti-CARD17 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CARD17 antibody
Suitable for use in ELISA and Western Blot.
Dilution: Peptide ELISA Titer: 1:8000
Western Blot: 0.5-1.5ug/ml ~15kD double band observed in Human Kidney and Lung lysates (calculated MW of 11.9kD according to NP_001007233.1).

Chemiluminescence of anti-CARD17 antibody

MBS627465 (0.5µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-CARD17 Polyclonal Antibody – Cat# MBS627465

Other Notes

Small volumes of anti-CARD17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CARD17. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
caspase recruitment domain-containing protein 17
NCBI Official Synonym Full Names
caspase recruitment domain family, member 17
NCBI Official Symbol
CARD17
NCBI Official Synonym Symbols
INCA
UniProt Protein Name
Caspase recruitment domain-containing protein 17
UniProt Synonym Protein Names
Caspase-1 inhibitor INCA; Inhibitory caspase recruitment domain protein
UniProt Gene Name
CARD17
UniProt Synonym Gene Names
INCA
UniProt Entry Name
CAR17_HUMAN
NCBI Protein Information
caspase recruitment domain-containing protein 17; Inhibitory CARD; OTTHUMP00000232067; caspase-1 inhibitor INCA; inhibitory caspase recruitment domain protein; inhibitory caspase recruitment domain (CARD) protein

UniProt Comments for CARD17

CARD17: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

Chromosomal Location of Human Ortholog: 11q22.3

Cellular Component: cytoplasm

Molecular Function: cysteine protease inhibitor activity

Biological Process: regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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