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CB086 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6281064

The C2ORF86 gene encodes an ortholog of Drosophila 'fritz,' a cytoplasmic WD40 repeat protein that controls planar cell polarity (summarized by Kim et al., 2010 [PubMed 20671153]). More details

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Product Overview

Online Datasheet in PDF
Product Name
CB086, Polyclonal Antibody
Full Product Name
CB086, CT (WDPCP, BBS15, C2orf86, FRITZ, WD repeat-containing and planar cell polarity effector protein fritz homolog, Bardet-Biedl syndrome 15 protein, WD repeat-containing and planar cell polarity effector protein) (MaxLight 550)
Product Gene Name
Product Synonym Gene Name
C2orf86
Product Synonym Names
WDPCP; BBS15; C2orf86; FRITZ; WD repeat-containing and planar cell polarity effector protein fritz homolog; Bardet-Biedl syndrome 15 protein; WD repeat-containing and planar cell polarity effector protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
66,655 Da
OMIM
217085
3D Structure
ModBase 3D Structure for O95876
Immunogen
CB086 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-709 amino acids from the C-terminal region of human CB086.
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-CB086 antibody

Applications Tested/Suitable for anti-CB086 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-CB086 antibody
IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-CB086 antibody

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Kim, S.K., et al. Science 329(5997):1337-1340(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009). Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008).

Other Notes

Small volumes of anti-CB086 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CB086 purchase

MBS6281064 is an antibody targeting CB086. Also known as CB086, CT (WDPCP, BBS15, C2orf86, FRITZ, WD repeat-containing and planar cell polarity effector protein fritz homolog, Bardet-Biedl syndrome 15 protein, WD repeat-containing and planar cell polarity effector protein) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CB086. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
WD repeat-containing and planar cell polarity effector protein fritz homolog isoform 2
NCBI Official Synonym Full Names
WD repeat containing planar cell polarity effector
NCBI Official Symbol
WDPCP
NCBI Official Synonym Symbols
FRTZ; BBS15; FRITZ; C2orf86
UniProt Protein Name
WD repeat-containing and planar cell polarity effector protein fritz homolog
UniProt Synonym Protein Names
Bardet-Biedl syndrome 15 protein; WD repeat-containing and planar cell polarity effector protein
UniProt Gene Name
WDPCP
UniProt Synonym Gene Names
BBS15; C2orf86; FRITZ; hFRTZ
NCBI Protein Information
WD repeat-containing and planar cell polarity effector protein fritz homolog; Bardet-Biedl syndrome 15 protein; WD repeat-containing protein C2orf86

UniProt Comments for CB086

Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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