Rabbit Anti-CD150 Polyclonal Antibody – Cat# MBS6468246

Dot blot analysis of anti-Phospho-SLAMF1-pY281 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

CD150 Antibody – Rabbit Polyclonal

Name: CD150 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6468246
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6468246

MBS6468246 is an antibody targeting CD150. Also known as CD150, Phosphorylated (Tyr281) (Signaling Lymphocytic Activation Molecule, IPO-3, CDw150, SLAMF1, SLAM) (PE). Reactive in Human. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD150, Polyclonal Antibody

Full Product Name

CD150, Phosphorylated (Tyr281) (Signaling Lymphocytic Activation Molecule, IPO-3, CDw150, SLAMF1, SLAM) (PE)

Product Gene Name

anti-CD150 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human SLAMF1 when phosphorylated at Tyr281.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

33,839 Da

OMIM

603492

3D Structure

ModBase 3D Structure for Q13291

Immunogen

Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr281 of human SLAMF1 (KLH).

Conjugate

Antigen Modification

Phosphorylated

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-CD150 antibody

Antibodies; CD Markers

Applications Tested/Suitable for anti-CD150 antibody

FLISA, Dot Blot (DB)

Application Notes for anti-CD150 antibody

FLISA: 1:1,000
Dot Blot: 1:500
Applications are based on unconjugated antibody.

Product References and Citations for anti-CD150 antibody

1. Mehrle, S., Mol. Immunol. 45(3), 796-804 (2008). 2. Howie, D., Blood 99(3), 957-965 (2002).

Other Notes

Small volumes of anti-CD150 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD150. It may not necessarily be applicable to this product.

NCBI GI #

4506969

NCBI GeneID

6504

NCBI Accession #

NP_003028

UniProt Primary Accession #

Q13291

UniProt Secondary Accession #

Q5W172; Q9HBE8

UniProt Related Accession #

Q13291

GenBank Nucleotide #

NM_003037.3

NCBI Official Full Name

signaling lymphocytic activation molecule

NCBI Official Synonym Full Names

signaling lymphocytic activation molecule family member 1

NCBI Official Symbol

SLAMF1

NCBI Official Synonym Symbols

SLAM; CD150; CDw150

UniProt Protein Name

Signaling lymphocytic activation molecule

UniProt Synonym Protein Names

CDw150; IPO-3; CD_antigen: CD150

Protein Family

Signaling lymphocytic activation molecule

UniProt Gene Name

SLAMF1

UniProt Synonym Gene Names

SLAM

UniProt Entry Name

SLAF1_HUMAN

NCBI Protein Information

signaling lymphocytic activation molecule; IPO-3

UniProt Comments for CD150

SLAM: a type I membrane protein present on the surface of B cells, T cells and CD83+ dendritic cells. A high-affinity self-ligand considered to be important in bidirectional T <-> B-cell stimulation. SLAM-induced signal-transduction events in T lymphocytes are different from those in B cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A (SAP) acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (SHP-2)-dependent signal transduction operates. Its cytoplasmic domain interacts with SAP through part of its SH2 domain, and with SHP-2. Three alternatively spliced isoforms have been described.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: integral to membrane; phagocytic vesicle; external side of plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; antigen binding

Biological Process: viral reproduction; regulation of catalytic activity; positive regulation of cell proliferation; regulation of vesicle fusion; lymphocyte activation; signal transduction

Research Articles on CD150

1. Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD150 antibody

Reference Product	PubMed Publications
FYN antibody	>4 publications with CD150 and FYN
SH2D1A antibody	>4 publications with CD150 and SH2D1A
UVRAG antibody	>2 publications with CD150 and UVRAG
BECN1 antibody	>2 publications with CD150 and BECN1
PTPRC antibody	>1 publications with CD150 and PTPRC
SH2D1B antibody	>1 publications with CD150 and SH2D1B

Pathways associated with anti-CD150 antibody

Products by Pathway	Pathway Diagram
Measles Pathway antibodies	Measles Pathway Diagram
Measles Pathway antibodies	Measles Pathway Diagram

Diseases associated with anti-CD150 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>4 publications with CD150 and Inflammation
Necrosis Antibodies	>4 publications with CD150 and Necrosis
Kidney Diseases Antibodies	>1 publications with CD150 and Kidney Diseases
Disease Models, Animal Antibodies	>1 publications with CD150 and Disease Models, Animal
Fetal Growth Retardation Antibodies	>1 publications with CD150 and Fetal Growth Retardation
Heart Diseases Antibodies	>1 publications with CD150 and Heart Diseases

Organs/Tissues associated with anti-CD150 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>23 publications with CD150 and Blood
Thymus Antibodies	>6 publications with CD150 and Thymus
Bone Antibodies	>5 publications with CD150 and Bone
Heart Antibodies	>2 publications with CD150 and Heart
Pharynx Antibodies	>1 publications with CD150 and Pharynx
Muscle Antibodies	>1 publications with CD150 and Muscle
Placenta Antibodies	>1 publications with CD150 and Placenta
Kidney Antibodies	>1 publications with CD150 and Kidney
Lymph Node Antibodies	>1 publications with CD150 and Lymph Node