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CD172b Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9242990

Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. More details

$475 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD172b, Polyclonal Antibody
Full Product Name
CD172b Polyclonal Antibody
Product Gene Name
Product Synonym Gene Name
SIRPB1
Product Synonym Names
SIRPB1; Signal-regulatory protein beta-1; SIRP-beta-1; CD172 antigen-like family member B; CD antigen CD172b
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
43,211 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (1545029..1600689, complement). Location: 20p13
OMIM
603889
3D Structure
ModBase 3D Structure for O00241
Applications Tested/Suitable for anti-CD172b antibody
Western Blot (WB)

Wester Blot (WB) of anti-CD172b antibody

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Rabbit Anti-CD172b Polyclonal Antibody – Cat# MBS9242990

Western Blot (WB) of anti-CD172b antibody

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Rabbit Anti-CD172b Polyclonal Antibody, Western Blot (WB) – Cat# MBS9242990

Other Notes

Small volumes of anti-CD172b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD172b purchase

MBS9242990 is an antibody targeting CD172b. Also known as CD172b Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD172b. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
signal-regulatory protein beta-1 isoform 2
NCBI Official Synonym Full Names
signal-regulatory protein beta 1
NCBI Official Symbol
SIRPB1
NCBI Official Synonym Symbols
CD172b; SIRP-BETA-1
UniProt Protein Name
Signal-regulatory protein beta-1
UniProt Synonym Protein Names
CD172 antigen-like family member B
UniProt Gene Name
SIRPB1
UniProt Synonym Gene Names
SIRP-beta-1
UniProt Entry Name
SIRB1_HUMAN
NCBI Protein Information
signal-regulatory protein beta-1; CD172 antigen-like family member B

NCBI Summary for CD172b

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
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UniProt Comments for CD172b

SIRPB1: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: integral to plasma membrane; integral to membrane; plasma membrane

Molecular Function: protein binding

Biological Process: cell surface receptor linked signal transduction; innate immune response; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD172b antibody

 Reference Product  PubMed Publications
 TYROBP antibody  >4 publications with CD172b and TYROBP
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