• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CD300b Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9246559

Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. More details

$475 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD300b, Polyclonal Antibody
Full Product Name
CD300b Polyclonal Antibody
Product Gene Name
anti-CD300b antibody
Product Synonym Names
CMRF35-like molecule 7 (CLM-7)(CD300 antigen-like family member B)(CMRF35-A2)(Immune receptor expressed on myeloid cells 3)(IREM-3)(Leukocyte mono-Ig-like receptor 5)(Triggering receptor expressed on myeloid cells 5)(TREM-5)(CD antigen CD300b)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
22,689 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (72516894..72527613, complement). Location: 17q25.1
OMIM
610705
3D Structure
ModBase 3D Structure for A8K4G0
Applications Tested/Suitable for anti-CD300b antibody
Immunohistochemistry-Paraffin (IHC-P)

Immunohistochemistry (IHC) of anti-CD300b antibody

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000
Rabbit Anti-CD300b Polyclonal Antibody – Cat# MBS9246559

Immunohistochemistry (IHC)-Paraffin of anti-CD300b antibody

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000
Rabbit Anti-CD300b Polyclonal Antibody, Immunohistochemistry (IHC)-Paraffin – Cat# MBS9246559

Immunohistochemistry (IHC)-Paraffin of anti-CD300b antibody

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000
Rabbit Anti-CD300b Polyclonal Antibody, Immunohistochemistry (IHC)-Paraffin – Cat# MBS9246559

Immunohistochemistry (IHC)-Paraffin of anti-CD300b antibody

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000
Rabbit Anti-CD300b Polyclonal Antibody, Immunohistochemistry (IHC)-Paraffin – Cat# MBS9246559

Other Notes

Small volumes of anti-CD300b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD300b purchase

MBS9246559 is an antibody targeting CD300b. Also known as CD300b Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD300b. It may not necessarily be applicable to this product.

NCBI GI #
510936990
NCBI GeneID
124599
NCBI Accession #
NP_777552.3
UniProt Primary Accession #
A8K4G0
UniProt Secondary Accession #
Q1EG73; Q8IX40; Q8N6D1
UniProt Related Accession #
A8K4G0
GenBank Nucleotide #
NM_174892.3
NCBI Official Full Name
CMRF35-like molecule 7
NCBI Official Synonym Full Names
CD300 molecule-like family member b
NCBI Official Symbol
CD300LB
NCBI Official Synonym Symbols
CLM7; CLM-7; IREM3; TREM5; CD300b; IREM-3; TREM-5; CMRF35-A2
UniProt Protein Name
CMRF35-like molecule 7
UniProt Synonym Protein Names
CD300 antigen-like family member B; CMRF35-A2; Immune receptor expressed on myeloid cells 3; IREM-3; Leukocyte mono-Ig-like receptor 5; Triggering receptor expressed on myeloid cells 5
Protein Family
CMRF35-like molecule
UniProt Gene Name
CD300LB
UniProt Synonym Gene Names
CD300B; CLM7; CMRF35A2; IREM3; LMIR5; TREM5; CLM-7; IREM-3; TREM-5
UniProt Entry Name
CLM7_HUMAN
NCBI Protein Information
CMRF35-like molecule 7; leukocyte mono-Ig-like receptor 5; CD300 antigen like family member B; immune receptor expressed on myeloid cells 3; triggering receptor expressed on myeloid cells 5

NCBI Summary for CD300b

CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008]

UniProt Comments for CD300b

Function: Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. Ref.1 Ref.9

Subunit structure: Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN. Ref.1 Ref.9

Subcellular location: Cell membrane; Single-pass type I membrane protein

By similarity.

Tissue specificity: Expressed exclusively in myeloid lineages. Ref.1

Post-translational modification: Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.

Sequence similarities: Belongs to the CD300 family.Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Sequence caution: The sequence AAH28091.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence BAF83614.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence EAW89170.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
Show more

Research Articles on CD300b

1. CD300 molecules are all expressed by DC; CD300b, d, e and f are restricted to different subpopulations of the myeloid DC lineage. They have been shown to regulate DC function both in vitro and in vivo.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD300b antibody

 Products by Pathway  Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram

Diseases associated with anti-CD300b antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with CD300b and Inflammation

Organs/Tissues associated with anti-CD300b antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with CD300b and Blood
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000