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CERS3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8591560

LASS3 is a 383 amino acid membrane protein almost exclusively expressed in testis, suggesting that LASS3 plays an important role in proper testis function. It is also weakly expressed in skin. A transcriptional variant of LASS3 cDNA exists and can result in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CERS3, Polyclonal Antibody
Full Product Name
CERS3 Antibody
Product Gene Name
Product Synonym Names
ARCI9; LASS3
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Purity/Purification
Antigen affinity purification.
Specificity
The antibody detects endogenous levels of total CERS3 protein.
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
Molecular Weight
46 kDa
Chromosome Location
Chromosome: 15; NC_000015.9 (100940600..101084925, complement). Location: 15q26.3
3D Structure
ModBase 3D Structure for Q8IU89
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human ceramide synthase 3

Product Categories/Family for anti-CERS3 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CERS3 antibody
Western Blot (WB)
Application Notes for anti-CERS3 antibody
WB: 1:200-1:1000

Other Notes

Small volumes of anti-CERS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CERS3 purchase

MBS8591560 is an antibody targeting CERS3. Also known as CERS3 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CERS3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ceramide synthase 3
NCBI Official Synonym Full Names
ceramide synthase 3
NCBI Official Symbol
CERS3
NCBI Official Synonym Symbols
LASS3
UniProt Protein Name
Ceramide synthase 3
UniProt Synonym Protein Names
LAG1 longevity assurance homolog 3
Protein Family
UniProt Gene Name
CERS3
UniProt Synonym Gene Names
LASS3; CerS3
UniProt Entry Name
CERS3_HUMAN
NCBI Protein Information
ceramide synthase 3; LAG1 homolog, ceramide synthase 3; LAG1 longevity assurance homolog 3

NCBI Summary for CERS3

This gene is a member of the ceramide synthase family of genes. The ceramide synthase enzymes regulate sphingolipid synthesis by catalyzing the formation of ceramides from sphingoid base and acyl-coA substrates. This family member is involved in the synthesis of ceramides with ultra-long-chain acyl moieties (ULC-Cers), important to the epidermis in its role in creating a protective barrier from the environment. The protein encoded by this gene has also been implicated in modification of the lipid structures required for spermatogenesis. Mutations in this gene have been associated with male fertility defects, and epidermal defects, including ichthyosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
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UniProt Comments for CERS3

Function: May be involved in sphingolipid synthesis or its regulation

By similarity.

Subcellular location: Nucleus membrane; Multi-pass membrane protein

Potential.

Sequence similarities: Contains 1 homeobox DNA-binding domain.Contains 1 TLC (TRAM/LAG1/CLN8) domain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CERS3 antibody

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