• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CHML Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3224469

This is a rabbit polyclonal antibody against CHML. It was validated on Western Blot using a cell lysate as a positive control.Target Description: The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CHML, Polyclonal Antibody
Full Product Name
CHML antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
REP2
Immunogen Sequence
Synthetic peptide located within the following region: NPSLGVSNTF TEVLDSALPE ESQLSYFNSD EMPAKHTQKS DTEISLEVTD
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CHML peptide (MBS3225100) is used for blocking the activity of CHML antibody (MBS3224469)
Molecular Weight
74kDa
OMIM
118825
3D Structure
ModBase 3D Structure for P26374
Homology
Human: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CHML

Product Categories/Family for anti-CHML antibody

Applications Tested/Suitable for anti-CHML antibody
Western Blot (WB)

Western Blot (WB) of anti-CHML antibody

WB Suggested Anti-CHML Antibody Titration: 0.05ug/ml
Positive Control: Jurkat cell lysate
Rabbit Anti-CHML Polyclonal Antibody – Cat# MBS3224469

Other Notes

Small volumes of anti-CHML antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHML purchase

MBS3224469 is an antibody targeting CHML. Also known as CHML antibody - N-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CHML. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rab proteins geranylgeranyltransferase component A 2
NCBI Official Synonym Full Names
CHM like Rab escort protein
NCBI Official Symbol
CHML
NCBI Official Synonym Symbols
REP2
UniProt Protein Name
Rab proteins geranylgeranyltransferase component A 2
UniProt Synonym Protein Names
Choroideremia-like protein; Rab escort protein 2
UniProt Gene Name
CHML
UniProt Synonym Gene Names
REP2; REP-2
UniProt Entry Name
RAE2_HUMAN
NCBI Protein Information
rab proteins geranylgeranyltransferase component A 2

NCBI Summary for CHML

The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. [provided by RefSeq, Jul 2008]

UniProt Comments for CHML

CHML: Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than REP-1 in supporting prenylation of Rab3 family. Belongs to the Rab GDI family.

Chromosomal Location of Human Ortholog: 1q43

Cellular Component: nucleoplasm; Rab-protein geranylgeranyltransferase complex; cytoplasm; cytosol

Molecular Function: GTPase activator activity; Rab GTPase binding; Rab-protein geranylgeranyltransferase activity

Biological Process: protein geranylgeranylation; intracellular protein transport; positive regulation of GTPase activity
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CHML antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000