Rabbit Anti-CHST12 Polyclonal Antibody – Cat# MBS6455137

CHST12 Antibody – Rabbit Polyclonal

Name: CHST12 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6455137
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6455137

MBS6455137 is an antibody targeting CHST12. Also known as CHST12 (Carbohydrate Sulfotransferase 12, Chondroitin 4-O-Sulfotransferase 2, Chondroitin 4-Sulfotransferase 2, C4ST-2, C4ST2, Sulfotransferase Hlo, CHST12) (MaxLight 750). Reactive in Human. Host:… More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CHST12, Polyclonal Antibody

Full Product Name

CHST12 (Carbohydrate Sulfotransferase 12, Chondroitin 4-O-Sulfotransferase 2, Chondroitin 4-Sulfotransferase 2, C4ST-2, C4ST2, Sulfotransferase Hlo, CHST12) (MaxLight 750)

Product Gene Name

anti-CHST12 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human CHST12. Species Crossreactivity: human

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

48,414 Da

3D Structure

ModBase 3D Structure for Q9NRB3

Immunogen

KLH conjugated synthetic peptide corresponding to aa72-106 at the N-terminal region of human CHST12.

Conjugate

MaxLight750

Note

Preservative Free

Product Categories/Family for anti-CHST12 antibody

Antibodies; Enzymes; Sulfotransferase

Applications Tested/Suitable for anti-CHST12 antibody

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Application Notes for anti-CHST12 antibody

WB: 1:2000
IHC-P: 1:25
Applications are based on unconjugated antibody.

Product References and Citations for anti-CHST12 antibody

Hiraoka N., et al. J. Biol. Chem. 275:20188-20196(2000). Xia G., et al. Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases. Clark H.F., et al. Genome Res. 13:2265-2270(2003). Ota T., et al. Nat. Genet. 36:40-45(2004). Scherer S.W., et al. Science 300:767-772(2003).

Other Notes

Small volumes of anti-CHST12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHST12. It may not necessarily be applicable to this product.

NCBI GI #

63102463

NCBI GeneID

55501

NCBI Accession #

AAH95492.1

UniProt Primary Accession #

Q9NRB3

UniProt Secondary Accession #

Q502W3; Q9NXY7; A4D1Z9

UniProt Related Accession #

Q9NRB3

NCBI Official Full Name

CHST12 protein

NCBI Official Synonym Full Names

carbohydrate sulfotransferase 12

NCBI Official Symbol

CHST12

NCBI Official Synonym Symbols

C4S-2; C4ST2; C4ST-2

UniProt Protein Name

Carbohydrate sulfotransferase 12

UniProt Synonym Protein Names

Chondroitin 4-O-sulfotransferase 2; Chondroitin 4-sulfotransferase 2; C4ST-2; C4ST2; Sulfotransferase Hlo

Protein Family

Carbohydrate sulfotransferase

UniProt Gene Name

CHST12

UniProt Synonym Gene Names

C4ST-2; C4ST2

NCBI Protein Information

carbohydrate sulfotransferase 12

NCBI Summary for CHST12

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011]

UniProt Comments for CHST12

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.

Research Articles on CHST12

1. These results have demonstrated that CHST11 and CHST13 negatively modulate metastasis and drug resistance of HCC cells probably via oncogenic MAPK signal pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CHST12 antibody

Products by Pathway	Pathway Diagram
Chondroitin Sulfate Biosynthesis Pathway antibodies	Chondroitin Sulfate Biosynthesis Pathway Diagram
Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies	Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies	Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram
Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies	Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
MPS I - Hurler Syndrome Pathway antibodies	MPS I - Hurler Syndrome Pathway Diagram
MPS II - Hunter Syndrome Pathway antibodies	MPS II - Hunter Syndrome Pathway Diagram
MPS IIIA - Sanfilippo Syndrome A Pathway antibodies	MPS IIIA - Sanfilippo Syndrome A Pathway Diagram
MPS IIIB - Sanfilippo Syndrome B Pathway antibodies	MPS IIIB - Sanfilippo Syndrome B Pathway Diagram