Rabbit Anti-CITED1 Polyclonal Antibody – Cat# MBS9608430

Western blot analysis of CITED1 using Jurkat whole lysates.

CITED1 Antibody – Rabbit Polyclonal

Name: CITED1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9608430
Price: 325 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9608430

Function: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator… More details

$325 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CITED1, Polyclonal Antibody

Full Product Name

CITED1 Antibody

Product Gene Name

anti-CITED1 antibody

Product Synonym Names

ABCC1; AI316840; AU019144; Cbp/p300-interacting transactivator 1; Cbp/p300-interacting transactivator with GLU/ASP-rich C-terminal domain, 1; Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1; CITE1_HUMAN; CITED1; melanocyte specific gene 1; Melanocyte specific protein 1; Melanocyte-specific protein 1; MSG1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purity/Purification

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.

Concentration

1mg/ml (lot specific)

Specificity

CITED1 antibody detects endogenous levels of total CITED1

Preparation and Storage

Store at -20 degree C. Stable for 12 months from date of receipt.

Antibody/Peptide Pairs

CITED1 peptide (MBS9627142) is used for blocking the activity of CITED1 antibody (MBS9608430)

Molecular Weight

Observed: 20 kDa
Predicted: 20 kDa

3D Structure

ModBase 3D Structure for Q99966

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Immunogen

A synthesized peptide derived from human CITED1

Subcellular Location

Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm by a nuclear export signal and (NES) in a CRM1-dependent manner.

Tissue Specificity

Expressed only in melanocytes and testis.

Conjugation

Unconjugated

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CITED1 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-CITED1 antibody

WB: 1:1000-3000

Other Notes

Small volumes of anti-CITED1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CITED1 purchase

MBS9608430 is an antibody targeting CITED1. Also known as CITED1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CITED1. It may not necessarily be applicable to this product.

NCBI GI #

222136688

NCBI GeneID

4435

NCBI Accession #

NP_001138357.1

UniProt Primary Accession #

Q99966

UniProt Secondary Accession #

B5BU50; B5BUI2

UniProt Related Accession #

Q99966

GenBank Nucleotide #

NM_001144885.1

NCBI Official Full Name

cbp/p300-interacting transactivator 1 isoform 2

NCBI Official Synonym Full Names

Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1

NCBI Official Symbol

CITED1

NCBI Official Synonym Symbols

MSG1

UniProt Protein Name

Cbp/p300-interacting transactivator 1

UniProt Synonym Protein Names

Melanocyte-specific protein 1

Protein Family

Cbp/p300-interacting transactivator

UniProt Gene Name

CITED1

UniProt Synonym Gene Names

MSG1

NCBI Protein Information

cbp/p300-interacting transactivator 1

NCBI Summary for CITED1

This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]

UniProt Comments for CITED1

Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.

Research Articles on CITED1

1. Forced nuclear enrichment of CITED1 in a human WT cell line appears to enhance tumorigenicity, whereas ectopic cytosolic expression confers stem-like properties and an embryonic phenotype.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CITED1 antibody

Reference Product	PubMed Publications
SMAD4 antibody	>7 publications with CITED1 and SMAD4
HSPA8 antibody	>1 publications with CITED1 and HSPA8
EP300 antibody	>1 publications with CITED1 and EP300

Pathways associated with anti-CITED1 antibody

Products by Pathway	Pathway Diagram
Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies	Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram
TGF-beta Receptor Signaling Pathway antibodies	TGF-beta Receptor Signaling Pathway Diagram

Diseases associated with anti-CITED1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>32 publications with CITED1 and Neoplasms
Head and Neck Neoplasms Antibodies	>19 publications with CITED1 and Head and Neck Neoplasms
Carcinoma Antibodies	>19 publications with CITED1 and Carcinoma
Endocrine Gland Neoplasms Antibodies	>18 publications with CITED1 and Endocrine Gland Neoplasms
Thyroid Neoplasms Antibodies	>18 publications with CITED1 and Thyroid Neoplasms
Melanoma Antibodies	>9 publications with CITED1 and Melanoma
Breast Neoplasms Antibodies	>5 publications with CITED1 and Breast Neoplasms
Disease Models, Animal Antibodies	>4 publications with CITED1 and Disease Models, Animal
Neoplasms, Experimental Antibodies	>3 publications with CITED1 and Neoplasms, Experimental
Pregnancy Complications Antibodies	>2 publications with CITED1 and Pregnancy Complications

Organs/Tissues associated with anti-CITED1 antibody

Organ/Tissue Name	Pubmed Publications
Thyroid Antibodies	>21 publications with CITED1 and Thyroid
Kidney Antibodies	>17 publications with CITED1 and Kidney
Embryonic Tissue Antibodies	>8 publications with CITED1 and Embryonic Tissue
Brain Antibodies	>4 publications with CITED1 and Brain
Skin Antibodies	>4 publications with CITED1 and Skin
Lung Antibodies	>2 publications with CITED1 and Lung
Ovary Antibodies	>2 publications with CITED1 and Ovary
Placenta Antibodies	>2 publications with CITED1 and Placenta
Pituitary Gland Antibodies	>1 publications with CITED1 and Pituitary Gland
Testis Antibodies	>1 publications with CITED1 and Testis