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CLVS2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9143048

Background: This gene encodes a protein that belongs to the SEC14/CRAL-TRIO family of proteins. A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes. [provided by RefSeq, Aug 2013] More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLVS2, Polyclonal Antibody
Full Product Name
CLVS2 Rabbit pAb
Product Gene Name
Product Synonym Names
C6orf212; C6orf213; RLBP1L2; bA160A10.4; CLVS2
Immunogen Sequence
LLDHEYDDDS EYNVDSYSMP VKEVEKELSP KSMKRSQSVV DPTVLKRMDK NEEENMQPLL SLD
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
38,000 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (123317582..123385063). Location: 6q22.31
3D Structure
ModBase 3D Structure for Q5SYC1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 265-327 of human CLVS2 (NP_001010852.2).
Positive Samples
U-87MG, U-251MG
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CLVS2 antibody
Western Blot (WB)
Application Notes for anti-CLVS2 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-CLVS2 antibody

Western blot analysis of extracts of various cell lines, using CLVS2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.
Rabbit Anti-CLVS2 Polyclonal Antibody – Cat# MBS9143048

Other Notes

Small volumes of anti-CLVS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLVS2 purchase

MBS9143048 is an antibody targeting CLVS2. Also known as CLVS2 Rabbit pAb. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CLVS2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Retinaldehyde binding protein 1-like 2
NCBI Official Synonym Full Names
clavesin 2
NCBI Official Symbol
CLVS2
NCBI Official Synonym Symbols
RLBP1L2; C6orf212; C6orf213; bA160A10.4
UniProt Protein Name
Clavesin-2
UniProt Synonym Protein Names
Retinaldehyde-binding protein 1-like 2
Protein Family
UniProt Gene Name
CLVS2
UniProt Synonym Gene Names
C6orf212; C6orf213; RLBP1L2
UniProt Entry Name
CLVS2_HUMAN
NCBI Protein Information
clavesin-2; retinaldehyde binding protein 1-like 2

NCBI Summary for CLVS2

This gene encodes a protein that belongs to the SEC14/CRAL-TRIO family of proteins. A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes. [provided by RefSeq, Aug 2013]

UniProt Comments for CLVS2

RLBP1L2: Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6q22.31

Cellular Component: clathrin-coated vesicle; early endosome membrane; trans-Golgi network; endosome

Molecular Function: transporter activity

Biological Process: transport; lysosome organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CLVS2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with CLVS2 and Brain
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