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CORO7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9429924

Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays a role in Golgi complex morphology and function. More details

$325 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CORO7, Polyclonal Antibody
Full Product Name
CORO7 Antibody
Product Gene Name
Product Synonym Names
CRN7; POD1; 0610011B16Rik
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Purity/Purification
Antigen affinity purification
Concentration
1mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total CORO7 protein.
Preparation and Storage
Store at -20 degree C.
Molecular Weight
101 kDa
OMIM
AK025674 mRNA
3D Structure
ModBase 3D Structure for P57737
Immunogen
Fusion protein of human CORO7
Immunogen Type
Protein

Product Categories/Family for anti-CORO7 antibody

Applications Tested/Suitable for anti-CORO7 antibody
Immunohistochemistry (IHC)
Application Notes for anti-CORO7 antibody
IF: 1: 25-100

Immunohistochemistry (IHC) of anti-CORO7 antibody

The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46955(CLEC12A Antibody) at dilution 1/20. (Original magnification: 200)
Rabbit Anti-CORO7 Polyclonal Antibody – Cat# MBS9429924

Other Notes

Small volumes of anti-CORO7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CORO7 purchase

MBS9429924 is an antibody targeting CORO7. Also known as CORO7 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CORO7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens coronin 7, mRNA
NCBI Official Synonym Full Names
coronin 7
NCBI Official Symbol
CORO7
NCBI Official Synonym Symbols
CRN7; POD1; 0610011B16Rik
UniProt Protein Name
Coronin-7
UniProt Synonym Protein Names
70 kDa WD repeat tumor rejection antigen homolog
Protein Family
UniProt Gene Name
CORO7
UniProt Synonym Gene Names
Crn7
NCBI Protein Information
coronin-7

NCBI Summary for CORO7

This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants; some of which form read-through transcripts with a neighboring gene. [provided by RefSeq, Dec 2016]
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UniProt Comments for CORO7

F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CORO7 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with CORO7 and Brain
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